Isacke CM - Search Results

1

Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host.

Jungwirth U, van Weverwijk A, Melake MJ, Chambers AF, Gao Q, Fivaz M, Isacke CM. Jungwirth U, et al. Among authors: isacke cm. Dis Model Mech. 2018 Jan 18;11(1):dmm031740. doi: 10.1242/dmm.031740. Dis Model Mech. 2018. PMID: 29208627 Free PMC article.

2

Endo180 (MRC2) Antibody-Drug Conjugate for the Treatment of Sarcoma.

Evans RJ, Perkins DW, Selfe J, Kelsey A, Birch GP, Shipley JM, Schipper K, Isacke CM. Evans RJ, et al. Among authors: isacke cm. Mol Cancer Ther. 2023 Feb 1;22(2):240-253. doi: 10.1158/1535-7163.MCT-22-0312. Mol Cancer Ther. 2023. PMID: 36399638 Free PMC article.

3

Pericytes promote selective vessel regression to regulate vascular patterning.

Simonavicius N, Ashenden M, van Weverwijk A, Lax S, Huso DL, Buckley CD, Huijbers IJ, Yarwood H, Isacke CM. Simonavicius N, et al. Among authors: isacke cm. Blood. 2012 Aug 16;120(7):1516-27. doi: 10.1182/blood-2011-01-332338. Epub 2012 Jun 27. Blood. 2012. PMID: 22740442 Free article.

4

GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors.

Morandi A, Martin LA, Gao Q, Pancholi S, Mackay A, Robertson D, Zvelebil M, Dowsett M, Plaza-Menacho I, Isacke CM. Morandi A, et al. Among authors: isacke cm. Cancer Res. 2013 Jun 15;73(12):3783-95. doi: 10.1158/0008-5472.CAN-12-4265. Epub 2013 May 6. Cancer Res. 2013. PMID: 23650283 Free PMC article.

5

An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor.

Murugaesu N, Iravani M, van Weverwijk A, Ivetic A, Johnson DA, Antonopoulos A, Fearns A, Jamal-Hanjani M, Sims D, Fenwick K, Mitsopoulos C, Gao Q, Orr N, Zvelebil M, Haslam SM, Dell A, Yarwood H, Lord CJ, Ashworth A, Isacke CM. Murugaesu N, et al. Among authors: isacke cm. Cancer Discov. 2014 Mar;4(3):304-17. doi: 10.1158/2159-8290.CD-13-0287. Epub 2014 Feb 11. Cancer Discov. 2014. PMID: 24520024

6

Mouse mammary stem cells express prognostic markers for triple-negative breast cancer.

Soady KJ, Kendrick H, Gao Q, Tutt A, Zvelebil M, Ordonez LD, Quist J, Tan DW, Isacke CM, Grigoriadis A, Smalley MJ. Soady KJ, et al. Among authors: isacke cm. Breast Cancer Res. 2015 Mar 4;17(1):31. doi: 10.1186/s13058-015-0539-6. Breast Cancer Res. 2015. PMID: 25849541 Free PMC article.

7

Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness.

Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, Hanby AM, Speirs V, Sahai E, Calvo F, Isacke CM. Avgustinova A, et al. Among authors: isacke cm. Nat Commun. 2016 Jan 18;7:10305. doi: 10.1038/ncomms10305. Nat Commun. 2016. PMID: 26777421 Free PMC article.

8

miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors.

Bacci M, Giannoni E, Fearns A, Ribas R, Gao Q, Taddei ML, Pintus G, Dowsett M, Isacke CM, Martin LA, Chiarugi P, Morandi A. Bacci M, et al. Among authors: isacke cm. Cancer Res. 2016 Mar 15;76(6):1615-26. doi: 10.1158/0008-5472.CAN-15-2038. Epub 2016 Jan 21. Cancer Res. 2016. PMID: 26795347

9

Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration.

Locard-Paulet M, Lim L, Veluscek G, McMahon K, Sinclair J, van Weverwijk A, Worboys JD, Yuan Y, Isacke CM, Jørgensen C. Locard-Paulet M, et al. Among authors: isacke cm. Sci Signal. 2016 Feb 9;9(414):ra15. doi: 10.1126/scisignal.aac5820. Sci Signal. 2016. PMID: 26861043 Free PMC article.

10

An In Vivo Functional Screen Identifies JNK Signaling As a Modulator of Chemotherapeutic Response in Breast Cancer.

Ashenden M, van Weverwijk A, Murugaesu N, Fearns A, Campbell J, Gao Q, Iravani M, Isacke CM. Ashenden M, et al. Among authors: isacke cm. Mol Cancer Ther. 2017 Sep;16(9):1967-1978. doi: 10.1158/1535-7163.MCT-16-0731. Epub 2017 Jun 13. Mol Cancer Ther. 2017. PMID: 28611109

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