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A new map of glycosaminoglycan and C3b binding sites on factor H.
Schmidt CQ, Herbert AP, Kavanagh D, Gandy C, Fenton CJ, Blaum BS, Lyon M, Uhrín D, Barlow PN. Schmidt CQ, et al. Among authors: kavanagh d. J Immunol. 2008 Aug 15;181(4):2610-9. doi: 10.4049/jimmunol.181.4.2610. J Immunol. 2008. PMID: 18684951
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.
Moore I, Strain L, Pappworth I, Kavanagh D, Barlow PN, Herbert AP, Schmidt CQ, Staniforth SJ, Holmes LV, Ward R, Morgan L, Goodship TH, Marchbank KJ. Moore I, et al. Among authors: kavanagh d. Blood. 2010 Jan 14;115(2):379-87. doi: 10.1182/blood-2009-05-221549. Epub 2009 Oct 27. Blood. 2010. PMID: 19861685 Free PMC article.
Structural basis for engagement by complement factor H of C3b on a self surface.
Morgan HP, Schmidt CQ, Guariento M, Blaum BS, Gillespie D, Herbert AP, Kavanagh D, Mertens HD, Svergun DI, Johansson CM, Uhrín D, Barlow PN, Hannan JP. Morgan HP, et al. Among authors: kavanagh d. Nat Struct Mol Biol. 2011 Apr;18(4):463-70. doi: 10.1038/nsmb.2018. Epub 2011 Feb 13. Nat Struct Mol Biol. 2011. PMID: 21317894 Free PMC article.
Factor H autoantibodies in membranoproliferative glomerulonephritis.
Goodship TH, Pappworth IY, Toth T, Denton M, Houlberg K, McCormick F, Warland D, Moore I, Hunze EM, Staniforth SJ, Hayes C, Cavalcante DP, Kavanagh D, Strain L, Herbert AP, Schmidt CQ, Barlow PN, Harris CL, Marchbank KJ. Goodship TH, et al. Among authors: kavanagh d. Mol Immunol. 2012 Oct;52(3-4):200-6. doi: 10.1016/j.molimm.2012.05.009. Epub 2012 Jun 20. Mol Immunol. 2012. PMID: 22721707
Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.
Wong EK, Anderson HE, Herbert AP, Challis RC, Brown P, Reis GS, Tellez JO, Strain L, Fluck N, Humphrey A, Macleod A, Richards A, Ahlert D, Santibanez-Koref M, Barlow PN, Marchbank KJ, Harris CL, Goodship TH, Kavanagh D. Wong EK, et al. Among authors: kavanagh d. J Am Soc Nephrol. 2014 Nov;25(11):2425-33. doi: 10.1681/ASN.2013070732. Epub 2014 Apr 10. J Am Soc Nephrol. 2014. PMID: 24722444 Free PMC article.
666 results