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Microglia ablation alleviates myelin-associated catatonic signs in mice.
Janova H, Arinrad S, Balmuth E, Mitjans M, Hertel J, Habes M, Bittner RA, Pan H, Goebbels S, Begemann M, Gerwig UC, Langner S, Werner HB, Kittel-Schneider S, Homuth G, Davatzikos C, Völzke H, West BL, Reif A, Grabe HJ, Boretius S, Ehrenreich H, Nave KA. Janova H, et al. J Clin Invest. 2018 Feb 1;128(2):734-745. doi: 10.1172/JCI97032. Epub 2017 Dec 18. J Clin Invest. 2018. PMID: 29252214 Free PMC article.
Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion.
Garcia-Agudo LF, Janova H, Sendler LE, Arinrad S, Steixner AA, Hassouna I, Balmuth E, Ronnenberg A, Schopf N, van der Flier FJ, Begemann M, Martens H, Weber MS, Boretius S, Nave KA, Ehrenreich H. Garcia-Agudo LF, et al. Among authors: janova h. FASEB J. 2019 Jul;33(7):8634-8647. doi: 10.1096/fj.201900337R. Epub 2019 May 15. FASEB J. 2019. PMID: 31090455
CD14 is a key organizer of microglial responses to CNS infection and injury.
Janova H, Böttcher C, Holtman IR, Regen T, van Rossum D, Götz A, Ernst AS, Fritsche C, Gertig U, Saiepour N, Gronke K, Wrzos C, Ribes S, Rolfes S, Weinstein J, Ehrenreich H, Pukrop T, Kopatz J, Stadelmann C, Salinas-Riester G, Weber MS, Prinz M, Brück W, Eggen BJ, Boddeke HW, Priller J, Hanisch UK. Janova H, et al. Glia. 2016 Apr;64(4):635-49. doi: 10.1002/glia.22955. Epub 2015 Dec 18. Glia. 2016. PMID: 26683584
Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism.
Menzfeld C, John M, van Rossum D, Regen T, Scheffel J, Janova H, Götz A, Ribes S, Nau R, Borisch A, Boutin P, Neumann K, Bremes V, Wienands J, Reichardt HM, Lühder F, Tischner D, Waetzig V, Herdegen T, Teismann P, Greig I, Müller M, Pukrop T, Mildner A, Kettenmann H, Brück W, Prinz M, Rotshenker S, Weber MS, Hanisch UK. Menzfeld C, et al. Among authors: janova h. Glia. 2015 Jun;63(6):1083-99. doi: 10.1002/glia.22803. Epub 2015 Mar 2. Glia. 2015. PMID: 25731696
Detection of Synaptic Proteins in Microglia by Flow Cytometry.
Brioschi S, d'Errico P, Amann LS, Janova H, Wojcik SM, Meyer-Luehmann M, Rajendran L, Wieghofer P, Paolicelli RC, Biber K. Brioschi S, et al. Among authors: janova h. Front Mol Neurosci. 2020 Sep 29;13:149. doi: 10.3389/fnmol.2020.00149. eCollection 2020. Front Mol Neurosci. 2020. PMID: 33132837 Free PMC article.
The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells.
Ribes S, Adam N, Schütze S, Regen T, Redlich S, Janova H, Borisch A, Hanisch UK, Nau R. Ribes S, et al. Among authors: janova h. J Neuroimmunol. 2012 Nov 15;252(1-2):16-23. doi: 10.1016/j.jneuroim.2012.07.012. Epub 2012 Aug 11. J Neuroimmunol. 2012. PMID: 22889567
Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down-regulated proportionally to neuronal loss in the human epileptic hippocampus.
Papageorgiou IE, Valous NA, Lahrmann B, Janova H, Klaft ZJ, Koch A, Schneider UC, Vajkoczy P, Heppner FL, Grabe N, Halama N, Heinemann U, Kann O. Papageorgiou IE, et al. Among authors: janova h. Glia. 2018 May;66(5):920-933. doi: 10.1002/glia.23292. Epub 2018 Jan 19. Glia. 2018. PMID: 29350438
Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing.
Schaafsma W, Zhang X, van Zomeren KC, Jacobs S, Georgieva PB, Wolf SA, Kettenmann H, Janova H, Saiepour N, Hanisch UK, Meerlo P, van den Elsen PJ, Brouwer N, Boddeke HW, Eggen BJ. Schaafsma W, et al. Among authors: janova h. Brain Behav Immun. 2015 Aug;48:205-21. doi: 10.1016/j.bbi.2015.03.013. Epub 2015 Apr 2. Brain Behav Immun. 2015. PMID: 25843371
16 results