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Small molecule inhibitor regorafenib inhibits RET signaling in neuroblastoma cells and effectively suppresses tumor growth in vivo.
Chen Z, Zhao Y, Yu Y, Pang JC, Woodfield SE, Tao L, Guan S, Zhang H, Bieerkehazhi S, Shi Y, Patel R, Vasudevan SA, Yi JS, Muscal JA, Xu GT, Yang J. Chen Z, et al. Among authors: yi js. Oncotarget. 2017 Oct 24;8(61):104090-104103. doi: 10.18632/oncotarget.22011. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262623 Free PMC article.
Defining the transcriptional control of pediatric AML highlights RARA as a superenhancer-regulated druggable dependency.
Perez MW, Sias-Garcia O, Daramola A, Wei H, Terrell M, Rashid R, Park WD, Duong K, Horton TM, Li F, Cherayil N, Koren JV, Gant VU, Junco JJ, Curry CV, Stevens AM, Lin CY, Yi JS. Perez MW, et al. Among authors: yi js. Blood Adv. 2021 Dec 14;5(23):4864-4876. doi: 10.1182/bloodadvances.2020003737. Blood Adv. 2021. PMID: 34543389 Free PMC article.
An oncogenic enhancer encodes selective selenium dependency in AML.
Eagle K, Jiang Y, Shi X, Li M, Obholzer NP, Hu T, Perez MW, Koren JV, Kitano A, Yi JS, Lin CY, Nakada D. Eagle K, et al. Among authors: yi js. Cell Stem Cell. 2022 Mar 3;29(3):386-399.e7. doi: 10.1016/j.stem.2022.01.003. Epub 2022 Feb 1. Cell Stem Cell. 2022. PMID: 35108519 Free PMC article.
Venetoclax for Acute Myeloid Leukemia in Pediatric Patients: A Texas Medical Center Experience.
Trabal A, Gibson A, He J, McCall D, Roth M, Nuñez C, Garcia M, Buzbee M, Toepfer L, Bidikian A, Daver N, Kadia T, Short NJ, Issa GC, Ravandi F, DiNardo CD, Montalban Bravo G, Garces S, Marcogliese A, Paek H, Dreyer Z, Brackett J, Redell M, Yi J, Garcia-Manero G, Konopleva M, Stevens A, Cuglievan B. Trabal A, et al. Cancers (Basel). 2023 Mar 26;15(7):1983. doi: 10.3390/cancers15071983. Cancers (Basel). 2023. PMID: 37046645 Free PMC article.
258 results