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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Ryan KJ, White CC, Patel K, Xu J, Olah M, Replogle JM, Frangieh M, Cimpean M, Winn P, McHenry A, Kaskow BJ, Chan G, Cuerdon N, Bennett DA, Boyd JD, Imitola J, Elyaman W, De Jager PL, Bradshaw EM. Ryan KJ, et al. Among authors: replogle jm. Sci Transl Med. 2017 Dec 20;9(421):eaai7635. doi: 10.1126/scitranslmed.aai7635. Sci Transl Med. 2017. PMID: 29263232 Free PMC article.
Interindividual variation in human T regulatory cells.
Ferraro A, D'Alise AM, Raj T, Asinovski N, Phillips R, Ergun A, Replogle JM, Bernier A, Laffel L, Stranger BE, De Jager PL, Mathis D, Benoist C. Ferraro A, et al. Among authors: replogle jm. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1111-20. doi: 10.1073/pnas.1401343111. Epub 2014 Mar 7. Proc Natl Acad Sci U S A. 2014. PMID: 24610777 Free PMC article.
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.
Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, McCabe C, Paik HI, Srivastava GP, Raychaudhuri S, Hafler DA, Koller D, Regev A, Hacohen N, Mathis D, Benoist C, Stranger BE, De Jager PL. Raj T, et al. Among authors: replogle jm. Science. 2014 May 2;344(6183):519-23. doi: 10.1126/science.1249547. Science. 2014. PMID: 24786080 Free PMC article.
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA. De Jager PL, et al. Nat Neurosci. 2014 Sep;17(9):1156-63. doi: 10.1038/nn.3786. Epub 2014 Aug 17. Nat Neurosci. 2014. PMID: 25129075 Free PMC article.
Epigenomics in translational research.
Replogle JM, De Jager PL. Replogle JM, et al. Transl Res. 2015 Jan;165(1):7-11. doi: 10.1016/j.trsl.2014.09.011. Epub 2014 Oct 5. Transl Res. 2015. PMID: 25445204 Free PMC article. No abstract available.
A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity.
Esposito F, Sorosina M, Ottoboni L, Lim ET, Replogle JM, Raj T, Brambilla P, Liberatore G, Guaschino C, Romeo M, Pertel T, Stankiewicz JM, Martinelli V, Rodegher M, Weiner HL, Brassat D, Benoist C, Patsopoulos NA, Comi G, Elyaman W, Martinelli Boneschi F, De Jager PL. Esposito F, et al. Among authors: replogle jm. Ann Neurol. 2015 Jul;78(1):115-27. doi: 10.1002/ana.24429. Epub 2015 May 14. Ann Neurol. 2015. PMID: 25914168
Reply: To PMID 25545807.
Replogle JM, De Jager PL. Replogle JM, et al. Ann Neurol. 2015 Oct;78(4):659-60. doi: 10.1002/ana.24456. Epub 2015 Aug 22. Ann Neurol. 2015. PMID: 26059823 No abstract available.
43 results