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Restoration of energy homeostasis by SIRT6 extends healthy lifespan.
Roichman A, Elhanati S, Aon MA, Abramovich I, Di Francesco A, Shahar Y, Avivi MY, Shurgi M, Rubinstein A, Wiesner Y, Shuchami A, Petrover Z, Lebenthal-Loinger I, Yaron O, Lyashkov A, Ubaida-Mohien C, Kanfi Y, Lerrer B, Fernández-Marcos PJ, Serrano M, Gottlieb E, de Cabo R, Cohen HY. Roichman A, et al. Among authors: di francesco a. Nat Commun. 2021 May 28;12(1):3208. doi: 10.1038/s41467-021-23545-7. Nat Commun. 2021. PMID: 34050173 Free PMC article.
Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
Mitchell SJ, Bernier M, Aon MA, Cortassa S, Kim EY, Fang EF, Palacios HH, Ali A, Navas-Enamorado I, Di Francesco A, Kaiser TA, Waltz TB, Zhang N, Ellis JL, Elliott PJ, Frederick DW, Bohr VA, Schmidt MS, Brenner C, Sinclair DA, Sauve AA, Baur JA, de Cabo R. Mitchell SJ, et al. Among authors: di francesco a. Cell Metab. 2018 Mar 6;27(3):667-676.e4. doi: 10.1016/j.cmet.2018.02.001. Cell Metab. 2018. PMID: 29514072 Free PMC article.
Yo-Yo Dieting is Better than None.
Di Germanio C, Di Francesco A, Bernier M, de Cabo R. Di Germanio C, et al. Among authors: di francesco a. Obesity (Silver Spring). 2018 Nov;26(11):1673. doi: 10.1002/oby.22335. Obesity (Silver Spring). 2018. PMID: 30358152 Free PMC article.
Disulfiram Treatment Normalizes Body Weight in Obese Mice.
Bernier M, Mitchell SJ, Wahl D, Diaz A, Singh A, Seo W, Wang M, Ali A, Kaiser T, Price NL, Aon MA, Kim EY, Petr MA, Cai H, Warren A, Di Germanio C, Di Francesco A, Fishbein K, Guiterrez V, Harney D, Koay YC, Mach J, Enamorado IN, Pulpitel T, Wang Y, Zhang J, Zhang L, Spencer RG, Becker KG, Egan JM, Lakatta EG, O'Sullivan J, Larance M, LeCouteur DG, Cogger VC, Gao B, Fernandez-Hernando C, Cuervo AM, de Cabo R. Bernier M, et al. Among authors: di francesco a, di germanio c. Cell Metab. 2020 Aug 4;32(2):203-214.e4. doi: 10.1016/j.cmet.2020.04.019. Epub 2020 May 14. Cell Metab. 2020. PMID: 32413333 Free PMC article.
Redox modulation of NQO1.
Siegel D, Dehn DD, Bokatzian SS, Quinn K, Backos DS, Di Francesco A, Bernier M, Reisdorph N, de Cabo R, Ross D. Siegel D, et al. Among authors: di francesco a. PLoS One. 2018 Jan 3;13(1):e0190717. doi: 10.1371/journal.pone.0190717. eCollection 2018. PLoS One. 2018. PMID: 29298345 Free PMC article.
NQO1 protects obese mice through improvements in glucose and lipid metabolism.
Di Francesco A, Choi Y, Bernier M, Zhang Y, Diaz-Ruiz A, Aon MA, Kalafut K, Ehrlich MR, Murt K, Ali A, Pearson KJ, Levan S, Preston JD, Martin-Montalvo A, Martindale JL, Abdelmohsen K, Michel CR, Willmes DM, Henke C, Navas P, Villalba JM, Siegel D, Gorospe M, Fritz K, Biswal S, Ross D, de Cabo R. Di Francesco A, et al. NPJ Aging Mech Dis. 2020 Nov 19;6(1):13. doi: 10.1038/s41514-020-00051-6. NPJ Aging Mech Dis. 2020. PMID: 33298924 Free PMC article.
A time to fast.
Di Francesco A, Di Germanio C, Bernier M, de Cabo R. Di Francesco A, et al. Among authors: di germanio c. Science. 2018 Nov 16;362(6416):770-775. doi: 10.1126/science.aau2095. Science. 2018. PMID: 30442801 Free PMC article. Review.
371 results