Machida M - Search Results

1

Knockout of the SREBP system increases production of the polyketide FR901512 in filamentous fungal sp. No. 14919 and lovastatin in Aspergillus terreus ATCC20542.

Itoh H, Miura A, Matsui M, Arazoe T, Nishida K, Kumagai T, Arita M, Tamano K, Machida M, Shibata T. Itoh H, et al. Among authors: machida m. Appl Microbiol Biotechnol. 2018 Feb;102(3):1393-1405. doi: 10.1007/s00253-017-8685-7. Epub 2017 Dec 21. Appl Microbiol Biotechnol. 2018. PMID: 29270733

2

Increased production of fatty acids and triglycerides in Aspergillus oryzae by enhancing expressions of fatty acid synthesis-related genes.

Tamano K, Bruno KS, Karagiosis SA, Culley DE, Deng S, Collett JR, Umemura M, Koike H, Baker SE, Machida M. Tamano K, et al. Among authors: machida m. Appl Microbiol Biotechnol. 2013 Jan;97(1):269-81. doi: 10.1007/s00253-012-4193-y. Epub 2012 Jun 26. Appl Microbiol Biotechnol. 2013. PMID: 22733113

3

Increased production of free fatty acids in Aspergillus oryzae by disruption of a predicted acyl-CoA synthetase gene.

Tamano K, Bruno KS, Koike H, Ishii T, Miura A, Umemura M, Culley DE, Baker SE, Machida M. Tamano K, et al. Among authors: machida m. Appl Microbiol Biotechnol. 2015 Apr;99(7):3103-13. doi: 10.1007/s00253-014-6336-9. Epub 2015 Jan 8. Appl Microbiol Biotechnol. 2015. PMID: 25564035

4

Further enhancement of FR901469 productivity by co-overexpression of cpcA, a cross-pathway control gene, and frbF in fungal sp. No. 11243.

Matsui M, Yokoyama T, Nemoto K, Kumagai T, Tamano K, Machida M, Shibata T. Matsui M, et al. Among authors: machida m. J Biosci Bioeng. 2017 Jul;124(1):8-14. doi: 10.1016/j.jbiosc.2017.02.015. Epub 2017 Mar 22. J Biosci Bioeng. 2017. PMID: 28341398

5

Biosynthesis of Novel Statins by Combining Heterologous Genes from Xylaria and Aspergillus.

Itoh H, Matsui M, Miyamura Y, Takeda I, Ishii J, Kumagai T, Machida M, Shibata T, Arita M. Itoh H, et al. Among authors: machida m. ACS Synth Biol. 2018 Dec 21;7(12):2783-2789. doi: 10.1021/acssynbio.8b00392. Epub 2018 Nov 13. ACS Synth Biol. 2018. PMID: 30403849 Free article.

6

Search for transcription factors affecting productivity of the polyketide FR901512 in filamentous fungal sp. No. 14919 and identification of Drf1, a novel negative regulator of the biosynthetic gene cluster.

Itoh H, Miura A, Takeda I, Matsui M, Tamano K, Machida M, Shibata T. Itoh H, et al. Among authors: machida m. Biosci Biotechnol Biochem. 2019 Jun;83(6):1163-1170. doi: 10.1080/09168451.2019.1584519. Epub 2019 Mar 1. Biosci Biotechnol Biochem. 2019. PMID: 30821612

7

Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitor FR901512.

Itoh H, Matsui M, Kumagai T, Arita M, Machida M, Shibata T. Itoh H, et al. Among authors: machida m. Genome Announc. 2017 Apr 6;5(14):e00129-17. doi: 10.1128/genomeA.00129-17. Genome Announc. 2017. PMID: 28385847 Free PMC article.

8

Genome Sequence of Fungal Species No.11243, Which Produces the Antifungal Antibiotic FR901469.

Matsui M, Yokoyama T, Nemoto K, Kumagai T, Terai G, Arita M, Machida M, Shibata T. Matsui M, et al. Among authors: machida m. Genome Announc. 2015 Apr 2;3(2):e00118-15. doi: 10.1128/genomeA.00118-15. Genome Announc. 2015. PMID: 25838475 Free PMC article.

9

Identification of a putative FR901469 biosynthesis gene cluster in fungal sp. No. 11243 and enhancement of the productivity by overexpressing the transcription factor gene frbF.

Matsui M, Yokoyama T, Nemoto K, Kumagai T, Terai G, Tamano K, Machida M, Shibata T. Matsui M, et al. Among authors: machida m. J Biosci Bioeng. 2017 Feb;123(2):147-153. doi: 10.1016/j.jbiosc.2016.08.007. Epub 2016 Sep 19. J Biosci Bioeng. 2017. PMID: 27660098

10

High-efficiency extracellular release of free fatty acids from Aspergillus oryzae using non-ionic surfactants.

Tamano K, Miura A, Koike H, Kamisaka Y, Umemura M, Machida M. Tamano K, et al. Among authors: machida m. J Biotechnol. 2017 Apr 20;248:9-14. doi: 10.1016/j.jbiotec.2017.03.002. Epub 2017 Mar 12. J Biotechnol. 2017. PMID: 28300661

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