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GABA(A)-current rundown of temporal lobe epilepsy is associated with repetitive activation of GABA(A) "phasic" receptors.
Palma E, Roseti C, Maiolino F, Fucile S, Martinello K, Mazzuferi M, Aronica E, Manfredi M, Esposito V, Cantore G, Miledi R, Simonato M, Eusebi F. Palma E, et al. Among authors: martinello k. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20944-8. doi: 10.1073/pnas.0710522105. Epub 2007 Dec 14. Proc Natl Acad Sci U S A. 2007. PMID: 18083839 Free PMC article.
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.
Roseti C, Martinello K, Fucile S, Piccari V, Mascia A, Di Gennaro G, Quarato PP, Manfredi M, Esposito V, Cantore G, Arcella A, Simonato M, Fredholm BB, Limatola C, Miledi R, Eusebi F. Roseti C, et al. Among authors: martinello k. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15118-23. doi: 10.1073/pnas.0807277105. Epub 2008 Sep 22. Proc Natl Acad Sci U S A. 2008. PMID: 18809912 Free PMC article.
Blockage of A2A and A3 adenosine receptors decreases the desensitization of human GABA(A) receptors microtransplanted to Xenopus oocytes.
Roseti C, Palma E, Martinello K, Fucile S, Morace R, Esposito V, Cantore G, Arcella A, Giangaspero F, Aronica E, Mascia A, Di Gennaro G, Quarato PP, Manfredi M, Cristalli G, Lambertucci C, Marucci G, Volpini R, Limatola C, Eusebi F. Roseti C, et al. Among authors: martinello k. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15927-31. doi: 10.1073/pnas.0907324106. Epub 2009 Aug 31. Proc Natl Acad Sci U S A. 2009. PMID: 19721003 Free PMC article.
Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy.
Mazzuferi M, Palma E, Martinello K, Maiolino F, Roseti C, Fucile S, Fabene PF, Schio F, Pellitteri M, Sperk G, Miledi R, Eusebi F, Simonato M. Mazzuferi M, et al. Among authors: martinello k. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3180-5. doi: 10.1073/pnas.0914710107. Epub 2010 Jan 26. Proc Natl Acad Sci U S A. 2010. PMID: 20133704 Free PMC article.
PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism.
Carnevale D, Vecchione C, Mascio G, Esposito G, Cifelli G, Martinello K, Landolfi A, Selvetella G, Grieco P, Damato A, Franco E, Haase H, Maffei A, Ciraolo E, Fucile S, Frati G, Mazzoni O, Hirsch E, Lembo G. Carnevale D, et al. Among authors: martinello k. Cardiovasc Res. 2012 Jan 1;93(1):200-9. doi: 10.1093/cvr/cvr288. Epub 2011 Oct 27. Cardiovasc Res. 2012. PMID: 22038741
Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy.
Roseti C, Fucile S, Lauro C, Martinello K, Bertollini C, Esposito V, Mascia A, Catalano M, Aronica E, Limatola C, Palma E. Roseti C, et al. Among authors: martinello k. Epilepsia. 2013 Oct;54(10):1834-44. doi: 10.1111/epi.12354. Epub 2013 Sep 13. Epilepsia. 2013. PMID: 24032743 Free article.
49 results