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Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.
Samson A, Scott KJ, Taggart D, West EJ, Wilson E, Nuovo GJ, Thomson S, Corns R, Mathew RK, Fuller MJ, Kottke TJ, Thompson JM, Ilett EJ, Cockle JV, van Hille P, Sivakumar G, Polson ES, Turnbull SJ, Appleton ES, Migneco G, Rose AS, Coffey MC, Beirne DA, Collinson FJ, Ralph C, Alan Anthoney D, Twelves CJ, Furness AJ, Quezada SA, Wurdak H, Errington-Mais F, Pandha H, Harrington KJ, Selby PJ, Vile RG, Griffin SD, Stead LF, Short SC, Melcher AA. Samson A, et al. Among authors: cockle jv. Sci Transl Med. 2018 Jan 3;10(422):eaam7577. doi: 10.1126/scitranslmed.aam7577. Sci Transl Med. 2018. PMID: 29298869 Free PMC article.
Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion.
Cockle JV, Brüning-Richardson A, Scott KJ, Thompson J, Kottke T, Morrison E, Ismail A, Carcaboso AM, Rose A, Selby P, Conner J, Picton S, Short S, Vile R, Melcher A, Ilett E. Cockle JV, et al. Mol Ther Oncolytics. 2017 May 2;5:75-86. doi: 10.1016/j.omto.2017.04.002. eCollection 2017 Jun 16. Mol Ther Oncolytics. 2017. PMID: 28547002 Free PMC article.
What is oncolytic virotherapy?
Cockle JV, Scott KJ. Cockle JV, et al. Arch Dis Child Educ Pract Ed. 2018 Feb;103(1):43-45. doi: 10.1136/archdischild-2016-311922. Epub 2017 Jun 6. Arch Dis Child Educ Pract Ed. 2018. PMID: 28588023 No abstract available.
FGFR1 Expression and Role in Migration in Low and High Grade Pediatric Gliomas.
Egbivwie N, Cockle JV, Humphries M, Ismail A, Esteves F, Taylor C, Karakoula K, Morton R, Warr T, Short SC, Brüning-Richardson A. Egbivwie N, et al. Among authors: cockle jv. Front Oncol. 2019 Mar 13;9:103. doi: 10.3389/fonc.2019.00103. eCollection 2019. Front Oncol. 2019. PMID: 30931252 Free PMC article.
Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity.
Grabovska Y, Mackay A, O'Hare P, Crosier S, Finetti M, Schwalbe EC, Pickles JC, Fairchild AR, Avery A, Cockle J, Hill R, Lindsey J, Hicks D, Kristiansen M, Chalker J, Anderson J, Hargrave D, Jacques TS, Straathof K, Bailey S, Jones C, Clifford SC, Williamson D. Grabovska Y, et al. Nat Commun. 2020 Aug 28;11(1):4324. doi: 10.1038/s41467-020-18070-y. Nat Commun. 2020. PMID: 32859926 Free PMC article.
14 results