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Page 1
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade.
Samson A, Scott KJ, Taggart D, West EJ, Wilson E, Nuovo GJ, Thomson S, Corns R, Mathew RK, Fuller MJ, Kottke TJ, Thompson JM, Ilett EJ, Cockle JV, van Hille P, Sivakumar G, Polson ES, Turnbull SJ, Appleton ES, Migneco G, Rose AS, Coffey MC, Beirne DA, Collinson FJ, Ralph C, Alan Anthoney D, Twelves CJ, Furness AJ, Quezada SA, Wurdak H, Errington-Mais F, Pandha H, Harrington KJ, Selby PJ, Vile RG, Griffin SD, Stead LF, Short SC, Melcher AA. Samson A, et al. Sci Transl Med. 2018 Jan 3;10(422):eaam7577. doi: 10.1126/scitranslmed.aam7577. Sci Transl Med. 2018. PMID: 29298869 Free PMC article.
Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition.
Jennings VA, Scott GB, Rose AMS, Scott KJ, Migneco G, Keller B, Reilly K, Donnelly O, Peach H, Dewar D, Harrington KJ, Pandha H, Samson A, Vile RG, Melcher AA, Errington-Mais F. Jennings VA, et al. Among authors: samson a. Mol Ther. 2019 Jun 5;27(6):1139-1152. doi: 10.1016/j.ymthe.2019.04.008. Epub 2019 Apr 14. Mol Ther. 2019. PMID: 31053413 Free PMC article.
Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21.
Müller LME, Holmes M, Michael JL, Scott GB, West EJ, Scott KJ, Parrish C, Hall K, Stäble S, Jennings VA, Cullen M, McConnell S, Langton C, Tidswell EL, Shafren D, Samson A, Harrington KJ, Pandha H, Ralph C, Kelly RJ, Cook G, Melcher AA, Errington-Mais F. Müller LME, et al. Among authors: samson a. J Immunother Cancer. 2019 Jul 1;7(1):164. doi: 10.1186/s40425-019-0632-y. J Immunother Cancer. 2019. PMID: 31262361 Free PMC article. Clinical Trial.
APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy.
Driscoll CB, Schuelke MR, Kottke T, Thompson JM, Wongthida P, Tonne JM, Huff AL, Miller A, Shim KG, Molan A, Wetmore C, Selby P, Samson A, Harrington K, Pandha H, Melcher A, Pulido JS, Harris R, Evgin L, Vile RG. Driscoll CB, et al. Among authors: samson a. Nat Commun. 2020 Feb 7;11(1):790. doi: 10.1038/s41467-020-14568-7. Nat Commun. 2020. PMID: 32034147 Free PMC article.
Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche.
Müller LME, Migneco G, Scott GB, Down J, King S, Askar B, Jennings V, Oyajobi B, Scott K, West E, Ralph C, Samson A, Ilett EJ, Muthana M, Coffey M, Melcher A, Parrish C, Cook G, Lawson M, Errington-Mais F. Müller LME, et al. Among authors: samson a. J Immunother Cancer. 2021 Mar;9(3):e001803. doi: 10.1136/jitc-2020-001803. J Immunother Cancer. 2021. PMID: 33741729 Free PMC article.
Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy.
Kottke T, Tonne J, Evgin L, Driscoll CB, van Vloten J, Jennings VA, Huff AL, Zell B, Thompson JM, Wongthida P, Pulido J, Schuelke MR, Samson A, Selby P, Ilett E, McNiven M, Roberts LR, Borad MJ, Pandha H, Harrington K, Melcher A, Vile RG. Kottke T, et al. Among authors: samson a. Nat Commun. 2021 Mar 26;12(1):1930. doi: 10.1038/s41467-021-22115-1. Nat Commun. 2021. PMID: 33772027 Free PMC article.
Immunotherapies for hepatocellular carcinoma.
Liu JKH, Irvine AF, Jones RL, Samson A. Liu JKH, et al. Among authors: samson a. Cancer Med. 2022 Feb;11(3):571-591. doi: 10.1002/cam4.4468. Epub 2021 Dec 24. Cancer Med. 2022. PMID: 34953051 Free PMC article. Review.
CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma.
Bozhanova G, Hassan J, Appleton L, Jennings V, Foo S, McLaughlin M, Chan Wah Hak CM, Patin EC, Crespo-Rodriguez E, Baker G, Armstrong E, Chiu M, Pandha H, Samson A, Roulstone V, Kyula J, Vile R, Errington-Mais F, Pedersen M, Harrington K, Ono M, Melcher A. Bozhanova G, et al. Among authors: samson a. J Immunother Cancer. 2022 Mar;10(3):e004410. doi: 10.1136/jitc-2021-004410. J Immunother Cancer. 2022. PMID: 35338089 Free PMC article.
417 results