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Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers.
Neuropharmacology. 2018 Jul 1;136(Pt A):92-101. doi: 10.1016/j.neuropharm.2017.12.042. Epub 2018 Jan 2.
Neuropharmacology. 2018.
PMID: 29305121
Free article.
The oligomeric state sets GABA(B) receptor signalling efficacy.
Comps-Agrar L, Kniazeff J, Nørskov-Lauritsen L, Maurel D, Gassmann M, Gregor N, Prézeau L, Bettler B, Durroux T, Trinquet E, Pin JP.
Comps-Agrar L, et al.
EMBO J. 2011 May 6;30(12):2336-49. doi: 10.1038/emboj.2011.143.
EMBO J. 2011.
PMID: 21552208
Free PMC article.
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N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization.
Nørskov-Lauritsen L, Jørgensen S, Bräuner-Osborne H.
Nørskov-Lauritsen L, et al.
FEBS Lett. 2015 Feb 27;589(5):588-97. doi: 10.1016/j.febslet.2015.01.019. Epub 2015 Jan 21.
FEBS Lett. 2015.
PMID: 25617829
Free article.
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Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor.
Jacobsen SE, Nørskov-Lauritsen L, Thomsen AR, Smajilovic S, Wellendorph P, Larsson NH, Lehmann A, Bhatia VK, Bräuner-Osborne H.
Jacobsen SE, et al.
J Pharmacol Exp Ther. 2013 Nov;347(2):298-309. doi: 10.1124/jpet.113.206276. Epub 2013 Sep 5.
J Pharmacol Exp Ther. 2013.
PMID: 24008333
Free PMC article.
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Selective Allosteric Antagonists for the G Protein-Coupled Receptor GPRC6A Based on the 2-Phenylindole Privileged Structure Scaffold.
Johansson H, Boesgaard MW, Nørskov-Lauritsen L, Larsen I, Kuhne S, Gloriam DE, Bräuner-Osborne H, Sejer Pedersen D.
Johansson H, et al.
J Med Chem. 2015 Nov 25;58(22):8938-51. doi: 10.1021/acs.jmedchem.5b01254. Epub 2015 Nov 16.
J Med Chem. 2015.
PMID: 26516782
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G protein-coupled receptor signaling analysis using homogenous time-resolved Förster resonance energy transfer (HTRF®) technology.
Nørskov-Lauritsen L, Thomsen AR, Bräuner-Osborne H.
Nørskov-Lauritsen L, et al.
Int J Mol Sci. 2014 Feb 13;15(2):2554-72. doi: 10.3390/ijms15022554.
Int J Mol Sci. 2014.
PMID: 24531140
Free PMC article.
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Role of post-translational modifications on structure, function and pharmacology of class C G protein-coupled receptors.
Nørskov-Lauritsen L, Bräuner-Osborne H.
Nørskov-Lauritsen L, et al.
Eur J Pharmacol. 2015 Sep 15;763(Pt B):233-40. doi: 10.1016/j.ejphar.2015.05.015. Epub 2015 May 14.
Eur J Pharmacol. 2015.
PMID: 25981296
Review.
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Structure of plant and fungal peroxidases.
Welinder KG, Mauro JM, Nørskov-Lauritsen L.
Welinder KG, et al.
Biochem Soc Trans. 1992 May;20(2):337-40. doi: 10.1042/bst0200337.
Biochem Soc Trans. 1992.
PMID: 1397625
Review.
No abstract available.
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