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Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
Zhou Q, Lehmer C, Michaelsen M, Mori K, Alterauge D, Baumjohann D, Schludi MH, Greiling J, Farny D, Flatley A, Feederle R, May S, Schreiber F, Arzberger T, Kuhm C, Klopstock T, Hermann A, Haass C, Edbauer D. Zhou Q, et al. Among authors: feederle r. EMBO Mol Med. 2017 May;9(5):687-702. doi: 10.15252/emmm.201607054. EMBO Mol Med. 2017. PMID: 28351931 Free PMC article.
Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD.
Lehmer C, Oeckl P, Weishaupt JH, Volk AE, Diehl-Schmid J, Schroeter ML, Lauer M, Kornhuber J, Levin J, Fassbender K, Landwehrmeyer B; German Consortium for Frontotemporal Lobar Degeneration; Schludi MH, Arzberger T, Kremmer E, Flatley A, Feederle R, Steinacker P, Weydt P, Ludolph AC, Edbauer D, Otto M. Lehmer C, et al. Among authors: feederle r. EMBO Mol Med. 2017 Jul;9(7):859-868. doi: 10.15252/emmm.201607486. EMBO Mol Med. 2017. PMID: 28408402 Free PMC article.
Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.
Ayoubian H, Fröhlich T, Pogodski D, Flatley A, Kremmer E, Schepers A, Feederle R, Arnold GJ, Grässer FA. Ayoubian H, et al. Among authors: feederle r. J Gen Virol. 2017 Aug;98(8):2128-2142. doi: 10.1099/jgv.0.000870. Epub 2017 Jul 28. J Gen Virol. 2017. PMID: 28758620
Pathological ASXL1 Mutations and Protein Variants Impair Neural Crest Development.
Matheus F, Rusha E, Rehimi R, Molitor L, Pertek A, Modic M, Feederle R, Flatley A, Kremmer E, Geerlof A, Rishko V, Rada-Iglesias A, Drukker M. Matheus F, et al. Among authors: feederle r. Stem Cell Reports. 2019 May 14;12(5):861-868. doi: 10.1016/j.stemcr.2019.03.006. Epub 2019 Apr 18. Stem Cell Reports. 2019. PMID: 31006630 Free PMC article.
Validation strategies for antibodies targeting modified ribonucleotides.
Weichmann F, Hett R, Schepers A, Ito-Kureha T, Flatley A, Slama K, Hastert FD, Angstman NB, Cardoso MC, König J, Hüttelmaier S, Dieterich C, Canzar S, Helm M, Heissmeyer V, Feederle R, Meister G. Weichmann F, et al. Among authors: feederle r. RNA. 2020 Oct;26(10):1489-1506. doi: 10.1261/rna.076026.120. Epub 2020 Jul 7. RNA. 2020. PMID: 32636310 Free PMC article.
Chemokine-like MDL proteins modulate flowering time and innate immunity in plants.
Gruner K, Leissing F, Sinitski D, Thieron H, Axstmann C, Baumgarten K, Reinstädler A, Winkler P, Altmann M, Flatley A, Jaouannet M, Zienkiewicz K, Feussner I, Keller H, Coustau C, Falter-Braun P, Feederle R, Bernhagen J, Panstruga R. Gruner K, et al. Among authors: feederle r. J Biol Chem. 2021 Jan-Jun;296:100611. doi: 10.1016/j.jbc.2021.100611. Epub 2021 Mar 30. J Biol Chem. 2021. PMID: 33798552 Free PMC article.
126 results