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Tie2 protects the vasculature against thrombus formation in systemic inflammation.
Higgins SJ, De Ceunynck K, Kellum JA, Chen X, Gu X, Chaudhry SA, Schulman S, Libermann TA, Lu S, Shapiro NI, Christiani DC, Flaumenhaft R, Parikh SM. Higgins SJ, et al. J Clin Invest. 2018 Apr 2;128(4):1471-1484. doi: 10.1172/JCI97488. Epub 2018 Mar 5. J Clin Invest. 2018. PMID: 29360642 Free PMC article. Clinical Trial.
Gene control of tyrosine kinase TIE2 and vascular manifestations of infections.
Ghosh CC, David S, Zhang R, Berghelli A, Milam K, Higgins SJ, Hunter J, Mukherjee A, Wei Y, Tran M, Suber F, Kobzik L, Kain KC, Lu S, Santel A, Yano K, Guha P, Dumont DJ, Christiani DC, Parikh SM. Ghosh CC, et al. Among authors: higgins sj. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2472-7. doi: 10.1073/pnas.1519467113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884170 Free PMC article.
PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury.
De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R. De Ceunynck K, et al. Among authors: higgins sj. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E982-E991. doi: 10.1073/pnas.1718600115. Epub 2018 Jan 17. Proc Natl Acad Sci U S A. 2018. PMID: 29343648 Free PMC article.
KLF2 and KLF4 control endothelial identity and vascular integrity.
Sangwung P, Zhou G, Nayak L, Chan ER, Kumar S, Kang DW, Zhang R, Liao X, Lu Y, Sugi K, Fujioka H, Shi H, Lapping SD, Ghosh CC, Higgins SJ, Parikh SM, Jo H, Jain MK. Sangwung P, et al. Among authors: higgins sj. JCI Insight. 2017 Feb 23;2(4):e91700. doi: 10.1172/jci.insight.91700. JCI Insight. 2017. PMID: 28239661 Free PMC article.
Connectivity-Dependent Conductance of 2,2'-Bipyridine-Based Metal Complexes.
Chelli Y, Ferri N, Vezzoli A, Davidson RJ, Morris J, Nichols RJ, Higgins SJ, Sangtarash S, Sadeghi H, Yufit DS, Beeby A. Chelli Y, et al. Among authors: higgins sj. ACS Omega. 2023 Dec 14;8(51):48958-48965. doi: 10.1021/acsomega.3c06555. eCollection 2023 Dec 26. ACS Omega. 2023. PMID: 38162767 Free PMC article.
136 results