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Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer.
Mohammad AS, Griffith JI, Adkins CE, Shah N, Sechrest E, Dolan EL, Terrell-Hall TB, Hendriks BS, Lee H, Lockman PR. Mohammad AS, et al. Among authors: adkins ce. Pharm Res. 2018 Jan 9;35(2):31. doi: 10.1007/s11095-017-2278-0. Pharm Res. 2018. PMID: 29368289 Free PMC article.
Molecular determinants of blood-brain barrier permeation.
Geldenhuys WJ, Mohammad AS, Adkins CE, Lockman PR. Geldenhuys WJ, et al. Among authors: adkins ce. Ther Deliv. 2015;6(8):961-71. doi: 10.4155/tde.15.32. Epub 2015 Aug 25. Ther Deliv. 2015. PMID: 26305616 Free PMC article. Review.
Alterations in Pericyte Subpopulations Are Associated with Elevated Blood-Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer.
Lyle LT, Lockman PR, Adkins CE, Mohammad AS, Sechrest E, Hua E, Palmieri D, Liewehr DJ, Steinberg SM, Kloc W, Izycka-Swieszewska E, Duchnowska R, Nayyar N, Brastianos PK, Steeg PS, Gril B. Lyle LT, et al. Among authors: adkins ce. Clin Cancer Res. 2016 Nov 1;22(21):5287-5299. doi: 10.1158/1078-0432.CCR-15-1836. Epub 2016 May 31. Clin Cancer Res. 2016. PMID: 27245829 Free PMC article.
Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer.
Lockman PR, Mittapalli RK, Taskar KS, Rudraraju V, Gril B, Bohn KA, Adkins CE, Roberts A, Thorsheim HR, Gaasch JA, Huang S, Palmieri D, Steeg PS, Smith QR. Lockman PR, et al. Among authors: adkins ce. Clin Cancer Res. 2010 Dec 1;16(23):5664-78. doi: 10.1158/1078-0432.CCR-10-1564. Epub 2010 Sep 9. Clin Cancer Res. 2010. PMID: 20829328 Free PMC article.
31 results