Fagan AM - Search Results

1

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study.

Gordon BA, Blazey TM, Su Y, Hari-Raj A, Dincer A, Flores S, Christensen J, McDade E, Wang G, Xiong C, Cairns NJ, Hassenstab J, Marcus DS, Fagan AM, Jack CR Jr, Hornbeck RC, Paumier KL, Ances BM, Berman SB, Brickman AM, Cash DM, Chhatwal JP, Correia S, Förster S, Fox NC, Graff-Radford NR, la Fougère C, Levin J, Masters CL, Rossor MN, Salloway S, Saykin AJ, Schofield PR, Thompson PM, Weiner MM, Holtzman DM, Raichle ME, Morris JC, Bateman RJ, Benzinger TLS. Gordon BA, et al. Among authors: fagan am. Lancet Neurol. 2018 Mar;17(3):241-250. doi: 10.1016/S1474-4422(18)30028-0. Epub 2018 Feb 1. Lancet Neurol. 2018. PMID: 29397305 Free PMC article.

2

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Neurobiol Dis. 2002 Apr;9(3):305-18. doi: 10.1006/nbdi.2002.0483. Neurobiol Dis. 2002. PMID: 11950276

3

Novel role for apolipoprotein E in the central nervous system. Modulation of sulfatide content.

Han X, Cheng H, Fryer JD, Fagan AM, Holtzman DM. Han X, et al. Among authors: fagan am. J Biol Chem. 2003 Mar 7;278(10):8043-51. doi: 10.1074/jbc.M212340200. Epub 2002 Dec 24. J Biol Chem. 2003. PMID: 12501252 Free article.

4

Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia.

Han X, Fagan AM, Cheng H, Morris JC, Xiong C, Holtzman DM. Han X, et al. Among authors: fagan am. Ann Neurol. 2003 Jul;54(1):115-9. doi: 10.1002/ana.10618. Ann Neurol. 2003. PMID: 12838527

5

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis.

Fagan AM, Christopher E, Taylor JW, Parsadanian M, Spinner M, Watson M, Fryer JD, Wahrle S, Bales KR, Paul SM, Holtzman DM. Fagan AM, et al. Am J Pathol. 2004 Oct;165(4):1413-22. doi: 10.1016/s0002-9440(10)63399-8. Am J Pathol. 2004. PMID: 15466405 Free PMC article.

6

Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-beta.

Morikawa M, Fryer JD, Sullivan PM, Christopher EA, Wahrle SE, DeMattos RB, O'Dell MA, Fagan AM, Lashuel HA, Walz T, Asai K, Holtzman DM. Morikawa M, et al. Among authors: fagan am. Neurobiol Dis. 2005 Jun-Jul;19(1-2):66-76. doi: 10.1016/j.nbd.2004.11.005. Neurobiol Dis. 2005. PMID: 15837562

7

Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid.

Hu Y, Malone JP, Fagan AM, Townsend RR, Holtzman DM. Hu Y, et al. Among authors: fagan am. Mol Cell Proteomics. 2005 Dec;4(12):2000-9. doi: 10.1074/mcp.M500207-MCP200. Epub 2005 Sep 30. Mol Cell Proteomics. 2005. PMID: 16199891 Free article.

8

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.

Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. Cirrito JR, et al. Among authors: fagan am. J Clin Invest. 2005 Nov;115(11):3285-90. doi: 10.1172/JCI25247. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239972 Free PMC article.

9

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

Fagan AM, Mintun MA, Mach RH, Lee SY, Dence CS, Shah AR, LaRossa GN, Spinner ML, Klunk WE, Mathis CA, DeKosky ST, Morris JC, Holtzman DM. Fagan AM, et al. Ann Neurol. 2006 Mar;59(3):512-9. doi: 10.1002/ana.20730. Ann Neurol. 2006. PMID: 16372280

10

The search for antecedent biomarkers of Alzheimer's disease.

Fagan AM, Csernansky CA, Morris JC, Holtzman DM. Fagan AM, et al. J Alzheimers Dis. 2005 Mar;8(4):347-58. doi: 10.3233/jad-2005-8404. J Alzheimers Dis. 2005. PMID: 16556966 Review.

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