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SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.
Mira E, Carmona-Rodríguez L, Pérez-Villamil B, Casas J, Fernández-Aceñero MJ, Martínez-Rey D, Martín-González P, Heras-Murillo I, Paz-Cabezas M, Tardáguila M, Oury TD, Martín-Puig S, Lacalle RA, Fabriás G, Díaz-Rubio E, Mañes S. Mira E, et al. Nat Commun. 2018 Feb 8;9(1):575. doi: 10.1038/s41467-018-03079-1. Nat Commun. 2018. PMID: 29422508 Free PMC article.
SOD3 induces a HIF-2α-dependent program in endothelial cells that provides a selective signal for tumor infiltration by T cells.
Carmona-Rodríguez L, Martínez-Rey D, Fernández-Aceñero MJ, González-Martín A, Paz-Cabezas M, Rodríguez-Rodríguez N, Pérez-Villamil B, Sáez ME, Díaz-Rubio E, Mira E, Mañes S. Carmona-Rodríguez L, et al. Among authors: mira e. J Immunother Cancer. 2020 Jun;8(1):e000432. doi: 10.1136/jitc-2019-000432. J Immunother Cancer. 2020. PMID: 32591431 Free PMC article.
Immunomodulatory and anti-inflammatory activities of statins.
Mira E, Mañes S. Mira E, et al. Endocr Metab Immune Disord Drug Targets. 2009 Sep;9(3):237-47. doi: 10.2174/187153009789044383. Epub 2009 Sep 1. Endocr Metab Immune Disord Drug Targets. 2009. PMID: 19594418 Review.
CX3CL1 promotes breast cancer via transactivation of the EGF pathway.
Tardáguila M, Mira E, García-Cabezas MA, Feijoo AM, Quintela-Fandino M, Azcoitia I, Lira SA, Mañes S. Tardáguila M, et al. Among authors: mira e. Cancer Res. 2013 Jul 15;73(14):4461-73. doi: 10.1158/0008-5472.CAN-12-3828. Epub 2013 May 29. Cancer Res. 2013. PMID: 23720051 Free PMC article.
Chemokine Receptor Signaling and the Hallmarks of Cancer.
Lacalle RA, Blanco R, Carmona-Rodríguez L, Martín-Leal A, Mira E, Mañes S. Lacalle RA, et al. Among authors: mira e. Int Rev Cell Mol Biol. 2017;331:181-244. doi: 10.1016/bs.ircmb.2016.09.011. Epub 2016 Nov 30. Int Rev Cell Mol Biol. 2017. PMID: 28325212 Review.
190 results