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Page 1
Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties.
Ribeiro Filho HV, Bernardi Videira N, Bridi AV, Tittanegro TH, Helena Batista FA, de Carvalho Pereira JG, de Oliveira PSL, Bajgelman MC, Le Maire A, Figueira ACM. Ribeiro Filho HV, et al. Among authors: figueira acm. Front Endocrinol (Lausanne). 2018 Feb 1;9:11. doi: 10.3389/fendo.2018.00011. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 29449830 Free PMC article.
Crystal Structure and Regulation of the Citrus Pol III Repressor MAF1 by Auxin and Phosphorylation.
Soprano AS, Giuseppe PO, Shimo HM, Lima TB, Batista FAH, Righetto GL, Pereira JGC, Granato DC, Nascimento AFZ, Gozzo FC, de Oliveira PSL, Figueira ACM, Smetana JHC, Paes Leme AF, Murakami MT, Benedetti CE. Soprano AS, et al. Among authors: figueira acm. Structure. 2017 Sep 5;25(9):1360-1370.e4. doi: 10.1016/j.str.2017.07.004. Epub 2017 Aug 3. Structure. 2017. PMID: 28781084 Free article.
Glutaminase Affects the Transcriptional Activity of Peroxisome Proliferator-Activated Receptor γ (PPARγ) via Direct Interaction.
de Guzzi Cassago CA, Dias MM, Pinheiro MP, Pasquali CC, Bastos ACS, Islam Z, Consonni SR, de Oliveira JF, Gomes EM, Ascenção CFR, Honorato R, Pauletti BA, Indolfo NC, Filho HVR, de Oliveira PSL, Figueira ACM, Paes Leme AF, Ambrosio ALB, Dias SMG. de Guzzi Cassago CA, et al. Among authors: figueira acm. Biochemistry. 2018 Nov 6;57(44):6293-6307. doi: 10.1021/acs.biochem.8b00773. Epub 2018 Oct 18. Biochemistry. 2018. PMID: 30295466
SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4.
Wong DVT, Ribeiro-Filho HV, Wanderley CWS, Leite CAVG, Lima JB, Assef ANB, Cajado AG, Batista GLP, González RH, Silva KO, Borges LPC, Alencar NMN, Wilke DV, Cunha TM, Figueira ACM, Cunha FQ, Lima-Júnior RCP. Wong DVT, et al. Among authors: figueira acm. Cancer Chemother Pharmacol. 2019 Aug;84(2):287-298. doi: 10.1007/s00280-019-03844-z. Epub 2019 Apr 22. Cancer Chemother Pharmacol. 2019. PMID: 31011814
GQ-130, a novel analogue of thiazolidinedione, improves obesity-induced metabolic alterations in rats: Evidence for the involvement of PPARβ/δ pathway.
Silva OA, Ribeiro-Filho HV, Avelino TM, Tittanegro TH, Figueira ACM, Rabelo LA, Pitta IDR, Lahlou S, Duarte GP. Silva OA, et al. Among authors: figueira acm. Clin Exp Pharmacol Physiol. 2020 May;47(5):798-808. doi: 10.1111/1440-1681.13252. Epub 2020 Jan 24. Clin Exp Pharmacol Physiol. 2020. PMID: 31909493
PPARγ S273 Phosphorylation Modifies the Dynamics of Coregulator Proteins Recruitment.
Dias MMG, Batista FAH, Tittanegro TH, de Oliveira AG, Le Maire A, Torres FR, Filho HVR, Silveira LR, Figueira ACM. Dias MMG, et al. Among authors: figueira acm. Front Endocrinol (Lausanne). 2020 Nov 27;11:561256. doi: 10.3389/fendo.2020.561256. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33329381 Free PMC article.
Structural dynamics of SARS-CoV-2 nucleocapsid protein induced by RNA binding.
Ribeiro-Filho HV, Jara GE, Batista FAH, Schleder GR, Costa Tonoli CC, Soprano AS, Guimarães SL, Borges AC, Cassago A, Bajgelman MC, Marques RE, Trivella DBB, Franchini KG, Figueira ACM, Benedetti CE, Lopes-de-Oliveira PS. Ribeiro-Filho HV, et al. Among authors: figueira acm. PLoS Comput Biol. 2022 May 12;18(5):e1010121. doi: 10.1371/journal.pcbi.1010121. eCollection 2022 May. PLoS Comput Biol. 2022. PMID: 35551296 Free PMC article.
Discovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor.
Mercaldi GF, Bezerra EHS, Batista FAH, Tonoli CCC, Soprano AS, Shimizu JF, Nagai A, da Silva JC, Filho HVR, do Nascimento Faria J, da Cunha MG, Zeri ACM, Nascimento AFZ, Proenca-Modena JL, Bajgelman MC, Rocco SA, Lopes-de-Oliveira PS, Cordeiro AT, Bruder M, Marques RE, Sforça ML, Franchini KG, Benedetti CE, Figueira ACM, Trivella DBB. Mercaldi GF, et al. Among authors: figueira acm. Sci Rep. 2022 Nov 2;12(1):18500. doi: 10.1038/s41598-022-22576-4. Sci Rep. 2022. PMID: 36323732 Free PMC article.
Unraveling the evolutionary origin of the complex Nuclear Receptor Element (cNRE), a cis-regulatory module required for preferential expression in the atrial chamber.
Nunes Santos L, Sousa Costa ÂM, Nikolov M, Carvalho JE, Coelho Sampaio A, Stockdale FE, Wang GF, Andrade Castillo H, Bortoletto Grizante M, Dudczig S, Vasconcelos M, Rosenthal N, Jusuf PR, Nim HT, de Oliveira P, Guimarães de Freitas Matos T, Nikovits W Jr, Tambones IL, Figueira ACM, Schubert M, Ramialison M, Xavier-Neto J. Nunes Santos L, et al. Among authors: figueira acm. Commun Biol. 2024 Apr 4;7(1):371. doi: 10.1038/s42003-024-05972-6. Commun Biol. 2024. PMID: 38575811 Free PMC article.
53 results