Long JZ - Search Results

1

Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration.

Lin H, Long JZ, Roche AM, Svensson KJ, Dou FY, Chang MR, Strutzenberg T, Ruiz C, Cameron MD, Novick SJ, Berdan CA, Louie SM, Nomura DK, Spiegelman BM, Griffin PR, Kamenecka TM. Lin H, et al. Among authors: long jz. J Med Chem. 2018 Apr 12;61(7):3224-3230. doi: 10.1021/acs.jmedchem.8b00029. Epub 2018 Mar 22. J Med Chem. 2018. PMID: 29533650 Free PMC article.

2

Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism.

Long JZ, Nomura DK, Cravatt BF. Long JZ, et al. Chem Biol. 2009 Jul 31;16(7):744-53. doi: 10.1016/j.chembiol.2009.05.009. Chem Biol. 2009. PMID: 19635411 Free PMC article.

3

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.

Long JZ, Nomura DK, Vann RE, Walentiny DM, Booker L, Jin X, Burston JJ, Sim-Selley LJ, Lichtman AH, Wiley JL, Cravatt BF. Long JZ, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20270-5. doi: 10.1073/pnas.0909411106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918051 Free PMC article.

4

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.

Nomura DK, Long JZ, Niessen S, Hoover HS, Ng SW, Cravatt BF. Nomura DK, et al. Among authors: long jz. Cell. 2010 Jan 8;140(1):49-61. doi: 10.1016/j.cell.2009.11.027. Cell. 2010. PMID: 20079333 Free PMC article.

5

Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases.

Long JZ, Jin X, Adibekian A, Li W, Cravatt BF. Long JZ, et al. J Med Chem. 2010 Feb 25;53(4):1830-42. doi: 10.1021/jm9016976. J Med Chem. 2010. PMID: 20099888 Free PMC article.

6

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system.

Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, Cravatt BF. Schlosburg JE, et al. Among authors: long jz. Nat Neurosci. 2010 Sep;13(9):1113-9. doi: 10.1038/nn.2616. Epub 2010 Aug 22. Nat Neurosci. 2010. PMID: 20729846 Free PMC article.

7

Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesics.

Ezzili C, Mileni M, McGlinchey N, Long JZ, Kinsey SG, Hochstatter DG, Stevens RC, Lichtman AH, Cravatt BF, Bilsky EJ, Boger DL. Ezzili C, et al. Among authors: long jz. J Med Chem. 2011 Apr 28;54(8):2805-22. doi: 10.1021/jm101597x. Epub 2011 Mar 23. J Med Chem. 2011. PMID: 21428410 Free PMC article.

8

Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice.

Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH. Ramesh D, et al. Among authors: long jz. J Pharmacol Exp Ther. 2011 Oct;339(1):173-85. doi: 10.1124/jpet.111.181370. Epub 2011 Jun 30. J Pharmacol Exp Ther. 2011. PMID: 21719468 Free PMC article.

9

Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer.

Nomura DK, Lombardi DP, Chang JW, Niessen S, Ward AM, Long JZ, Hoover HH, Cravatt BF. Nomura DK, et al. Among authors: long jz. Chem Biol. 2011 Jul 29;18(7):846-56. doi: 10.1016/j.chembiol.2011.05.009. Chem Biol. 2011. PMID: 21802006 Free PMC article.

10

Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation.

Nomura DK, Morrison BE, Blankman JL, Long JZ, Kinsey SG, Marcondes MC, Ward AM, Hahn YK, Lichtman AH, Conti B, Cravatt BF. Nomura DK, et al. Among authors: long jz. Science. 2011 Nov 11;334(6057):809-13. doi: 10.1126/science.1209200. Epub 2011 Oct 20. Science. 2011. PMID: 22021672 Free PMC article.

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