McCormack E - Search Results

1

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S. Ladds MJGW, et al. Among authors: mccormack e. Nat Commun. 2018 Mar 16;9(1):1107. doi: 10.1038/s41467-018-03441-3. Nat Commun. 2018. PMID: 29549331 Free PMC article.

2

Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines.

Silden E, Hjelle SM, Wergeland L, Sulen A, Andresen V, Bourdon JC, Micklem DR, McCormack E, Gjertsen BT. Silden E, et al. Among authors: mccormack e. PLoS One. 2013;8(2):e56276. doi: 10.1371/journal.pone.0056276. Epub 2013 Feb 11. PLoS One. 2013. PMID: 23409163 Free PMC article.

3

Sonoporation-enhanced chemotherapy significantly reduces primary tumour burden in an orthotopic pancreatic cancer xenograft.

Kotopoulis S, Delalande A, Popa M, Mamaeva V, Dimcevski G, Gilja OH, Postema M, Gjertsen BT, McCormack E. Kotopoulis S, et al. Among authors: mccormack e. Mol Imaging Biol. 2014 Feb;16(1):53-62. doi: 10.1007/s11307-013-0672-5. Mol Imaging Biol. 2014. PMID: 23877869

4

First in-mouse development and application of a surgically relevant xenograft model of ovarian carcinoma.

Helland O, Popa M, Vintermyr OK, Molven A, Gjertsen BT, Bjørge L, McCormack E. Helland O, et al. Among authors: mccormack e. PLoS One. 2014 Mar 4;9(3):e89527. doi: 10.1371/journal.pone.0089527. eCollection 2014. PLoS One. 2014. PMID: 24594904 Free PMC article.

5

Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia.

Haaland I, Opsahl JA, Berven FS, Reikvam H, Fredly HK, Haugse R, Thiede B, McCormack E, Lain S, Bruserud O, Gjertsen BT. Haaland I, et al. Among authors: mccormack e. Mol Cancer. 2014 May 21;13:116. doi: 10.1186/1476-4598-13-116. Mol Cancer. 2014. PMID: 24885082 Free PMC article.

6

SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.

Li L, Osdal T, Ho Y, Chun S, McDonald T, Agarwal P, Lin A, Chu S, Qi J, Li L, Hsieh YT, Dos Santos C, Yuan H, Ha TQ, Popa M, Hovland R, Bruserud Ø, Gjertsen BT, Kuo YH, Chen W, Lain S, McCormack E, Bhatia R. Li L, et al. Among authors: mccormack e. Cell Stem Cell. 2014 Oct 2;15(4):431-446. doi: 10.1016/j.stem.2014.08.001. Cell Stem Cell. 2014. PMID: 25280219 Free PMC article.

7

Xenograft Models of Primary Acute Myeloid Leukemia for the Development of Imaging Strategies and Evaluation of Novel Targeted Therapies.

Gelebart P, Popa M, McCormack E. Gelebart P, et al. Among authors: mccormack e. Curr Pharm Biotechnol. 2016;17(1):42-51. doi: 10.2174/1389201016666150817095703. Curr Pharm Biotechnol. 2016. PMID: 26278528 Review.

8

The HDACi Panobinostat Shows Growth Inhibition Both In Vitro and in a Bioluminescent Orthotopic Surgical Xenograft Model of Ovarian Cancer.

Helland Ø, Popa M, Bischof K, Gjertsen BT, McCormack E, Bjørge L. Helland Ø, et al. Among authors: mccormack e. PLoS One. 2016 Jun 28;11(6):e0158208. doi: 10.1371/journal.pone.0158208. eCollection 2016. PLoS One. 2016. PMID: 27352023 Free PMC article.

9

Sonoporation with Acoustic Cluster Therapy (ACT®) induces transient tumour volume reduction in a subcutaneous xenograft model of pancreatic ductal adenocarcinoma.

Kotopoulis S, Stigen E, Popa M, Safont MM, Healey A, Kvåle S, Sontum P, Gjertsen BT, Gilja OH, McCormack E. Kotopoulis S, et al. Among authors: mccormack e. J Control Release. 2017 Jan 10;245:70-80. doi: 10.1016/j.jconrel.2016.11.019. Epub 2016 Nov 18. J Control Release. 2017. PMID: 27871988

10

Anti-proliferative activity of the NPM1 interacting natural product avrainvillamide in acute myeloid leukemia.

Andresen V, Erikstein BS, Mukherjee H, Sulen A, Popa M, Sørnes S, Reikvam H, Chan KP, Hovland R, McCormack E, Bruserud Ø, Myers AG, Gjertsen BT. Andresen V, et al. Among authors: mccormack e. Cell Death Dis. 2016 Dec 1;7(12):e2497. doi: 10.1038/cddis.2016.392. Cell Death Dis. 2016. PMID: 27906185 Free PMC article.

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