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The -2518 A/G polymorphism of the monocyte chemoattractant protein-1 as a candidate genetic predisposition factor for secondary myelofibrosis and biomarker of disease severity.
Masselli E, Carubbi C, Cambò B, Pozzi G, Gobbi G, Mirandola P, Follini E, Pagliaro L, Di Marcantonio D, Bonatti F, Percesepe A, Sykes SM, Aversa F, Vitale M. Masselli E, et al. Among authors: sykes sm. Leukemia. 2018 Oct;32(10):2266-2270. doi: 10.1038/s41375-018-0088-y. Epub 2018 Mar 6. Leukemia. 2018. PMID: 29568096 Free PMC article. No abstract available.
Proplatelet generation in the mouse requires PKCε-dependent RhoA inhibition.
Gobbi G, Mirandola P, Carubbi C, Masselli E, Sykes SM, Ferraro F, Nouvenne A, Thon JN, Italiano JE Jr, Vitale M. Gobbi G, et al. Among authors: sykes sm. Blood. 2013 Aug 15;122(7):1305-11. doi: 10.1182/blood-2013-04-490599. Epub 2013 Jul 9. Blood. 2013. PMID: 23838351 Free PMC article.
PKCε as a novel promoter of skeletal muscle differentiation and regeneration.
Di Marcantonio D, Galli D, Carubbi C, Gobbi G, Queirolo V, Martini S, Merighi S, Vaccarezza M, Maffulli N, Sykes SM, Vitale M, Mirandola P. Di Marcantonio D, et al. Among authors: sykes sm. Exp Cell Res. 2015 Nov 15;339(1):10-9. doi: 10.1016/j.yexcr.2015.09.017. Epub 2015 Sep 30. Exp Cell Res. 2015. PMID: 26431586 Free PMC article.
Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia.
Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Fröhling S, Balachandran S, Skorski T, Garcia BA, Mirandola P, Gobbi G, Garzon R, Vitale M, Sykes SM. Di Marcantonio D, et al. Among authors: sykes sm. Clin Cancer Res. 2018 Feb 1;24(3):608-618. doi: 10.1158/1078-0432.CCR-17-2684. Epub 2017 Nov 10. Clin Cancer Res. 2018. PMID: 29127121 Free PMC article.
MLL-AF9 leukemias are sensitive to PARP1 inhibitors combined with cytotoxic drugs.
Maifrede S, Martinez E, Nieborowska-Skorska M, Di Marcantonio D, Hulse M, Le BV, Zhao H, Piwocka K, Tempera I, Sykes SM, Skorski T. Maifrede S, et al. Among authors: sykes sm. Blood Adv. 2017 Aug 9;1(19):1467-1472. doi: 10.1182/bloodadvances.2017006247. eCollection 2017 Aug 22. Blood Adv. 2017. PMID: 29296788 Free PMC article.
RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia.
Rudat S, Pfaus A, Cheng YY, Holtmann J, Ellegast JM, Bühler C, Marcantonio DD, Martinez E, Göllner S, Wickenhauser C, Müller-Tidow C, Lutz C, Bullinger L, Milsom MD, Sykes SM, Fröhling S, Scholl C. Rudat S, et al. Among authors: sykes sm. Leukemia. 2018 Oct;32(10):2189-2202. doi: 10.1038/s41375-018-0102-4. Epub 2018 Mar 22. Leukemia. 2018. PMID: 29654265
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance.
Nacson J, Krais JJ, Bernhardy AJ, Clausen E, Feng W, Wang Y, Nicolas E, Cai KQ, Tricarico R, Hua X, DiMarcantonio D, Martinez E, Zong D, Handorf EA, Bellacosa A, Testa JR, Nussenzweig A, Gupta GP, Sykes SM, Johnson N. Nacson J, et al. Among authors: sykes sm. Cell Rep. 2018 Sep 25;24(13):3513-3527.e7. doi: 10.1016/j.celrep.2018.08.086. Cell Rep. 2018. PMID: 30257212 Free PMC article.
BRCA1 Mutational Complementation Induces Synthetic Viability.
Nacson J, Di Marcantonio D, Wang Y, Bernhardy AJ, Clausen E, Hua X, Cai KQ, Martinez E, Feng W, Callén E, Wu W, Gupta GP, Testa JR, Nussenzweig A, Sykes SM, Johnson N. Nacson J, et al. Among authors: sykes sm. Mol Cell. 2020 Jun 4;78(5):951-959.e6. doi: 10.1016/j.molcel.2020.04.006. Epub 2020 Apr 30. Mol Cell. 2020. PMID: 32359443 Free PMC article.
71 results