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Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors.
J Biol Chem. 2018 May 25;293(21):8173-8181. doi: 10.1074/jbc.RA118.002835. Epub 2018 Apr 13.
J Biol Chem. 2018.
PMID: 29653944
Free PMC article.
Transcriptome analysis of the distal small intestine of Cftr null mice.
Ikpa PT, Meijsen KF, Nieuwenhuijze NDA, Dulla K, de Jonge HR, Bijvelds MJC.
Ikpa PT, et al. Among authors: nieuwenhuijze nda.
Genomics. 2020 Mar;112(2):1139-1150. doi: 10.1016/j.ygeno.2019.06.028. Epub 2019 Jun 25.
Genomics. 2020.
PMID: 31251978
Free article.
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Impaired Intestinal Farnesoid X Receptor Signaling in Cystic Fibrosis Mice.
Ikpa PT, Doktorova M, Meijsen KF, Nieuwenhuijze NDA, Verkade HJ, Jonker JW, de Jonge HR, Bijvelds MJC.
Ikpa PT, et al. Among authors: nieuwenhuijze nda.
Cell Mol Gastroenterol Hepatol. 2020;9(1):47-60. doi: 10.1016/j.jcmgh.2019.08.006. Epub 2019 Aug 27.
Cell Mol Gastroenterol Hepatol. 2020.
PMID: 31470114
Free PMC article.
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Targeted locus amplification reveals heterogeneity between and within CFTR genotypes and association with CFTR function in patient-derived intestinal organoids.
Lefferts JW, Boersma V, Nieuwenhuijze NDA, Suen SWF, Hajo K, Collantes NS, Vermeulen C, Groeneweg T, Hagemeijer MC, de Jonge HR, van der Ent CK, Splinter E, Beekman JM.
Lefferts JW, et al. Among authors: nieuwenhuijze nda.
J Cyst Fibros. 2023 May;22(3):538-547. doi: 10.1016/j.jcf.2023.04.003. Epub 2023 Apr 24.
J Cyst Fibros. 2023.
PMID: 37100706
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OrgaSegment: deep-learning based organoid segmentation to quantify CFTR dependent fluid secretion.
Lefferts JW, Kroes S, Smith MB, Niemöller PJ, Nieuwenhuijze NDA, Sonneveld van Kooten HN, van der Ent CK, Beekman JM, van Beuningen SFB.
Lefferts JW, et al. Among authors: nieuwenhuijze nda.
Commun Biol. 2024 Mar 13;7(1):319. doi: 10.1038/s42003-024-05966-4.
Commun Biol. 2024.
PMID: 38480810
Free PMC article.
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CFTR Function Restoration upon Elexacaftor/Tezacaftor/Ivacaftor Treatment in Patient-Derived Intestinal Organoids with Rare CFTR Genotypes.
Lefferts JW, Bierlaagh MC, Kroes S, Nieuwenhuijze NDA, Sonneveld van Kooten HN, Niemöller PJ, Verburg TF, Janssens HM, Muilwijk D, van Beuningen SFB, van der Ent CK, Beekman JM.
Lefferts JW, et al. Among authors: nieuwenhuijze nda.
Int J Mol Sci. 2023 Sep 26;24(19):14539. doi: 10.3390/ijms241914539.
Int J Mol Sci. 2023.
PMID: 37833986
Free PMC article.
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