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Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling.
Lee JV, Berry CT, Kim K, Sen P, Kim T, Carrer A, Trefely S, Zhao S, Fernandez S, Barney LE, Schwartz AD, Peyton SR, Snyder NW, Berger SL, Freedman BD, Wellen KE. Lee JV, et al. Among authors: berger sl. Genes Dev. 2018 Apr 1;32(7-8):497-511. doi: 10.1101/gad.311027.117. Epub 2018 Apr 19. Genes Dev. 2018. PMID: 29674394 Free PMC article.
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications.
Nathan D, Ingvarsdottir K, Sterner DE, Bylebyl GR, Dokmanovic M, Dorsey JA, Whelan KA, Krsmanovic M, Lane WS, Meluh PB, Johnson ES, Berger SL. Nathan D, et al. Among authors: berger sl. Genes Dev. 2006 Apr 15;20(8):966-76. doi: 10.1101/gad.1404206. Epub 2006 Apr 5. Genes Dev. 2006. PMID: 16598039 Free PMC article.
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.
Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M. Shema E, et al. Among authors: berger sl. Genes Dev. 2008 Oct 1;22(19):2664-76. doi: 10.1101/gad.1703008. Genes Dev. 2008. PMID: 18832071 Free PMC article.
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.
Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J, Huang P, Sawyer SK, Fuerth B, Faubert B, Kalliomäki T, Elia A, Luo X, Nadeem V, Bungard D, Yalavarthi S, Growney JD, Wakeham A, Moolani Y, Silvester J, Ten AY, Bakker W, Tsuchihara K, Berger SL, Hill RP, Jones RG, Tsao M, Robinson MO, Thompson CB, Pan G, Mak TW. Zaugg K, et al. Among authors: berger sl. Genes Dev. 2011 May 15;25(10):1041-51. doi: 10.1101/gad.1987211. Genes Dev. 2011. PMID: 21576264 Free PMC article.
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, Mellinghoff IK, Thompson CB. Lu C, et al. Among authors: berger sl. Nature. 2012 Feb 15;483(7390):474-8. doi: 10.1038/nature10860. Nature. 2012. PMID: 22343901 Free PMC article.
311 results