Saiakhova A - Search Results

1

Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis.

Forrest ME, Saiakhova A, Beard L, Buchner DA, Scacheri PC, LaFramboise T, Markowitz S, Khalil AM. Forrest ME, et al. Among authors: saiakhova a. Sci Rep. 2018 May 9;8(1):7324. doi: 10.1038/s41598-018-25530-5. Sci Rep. 2018. PMID: 29743621 Free PMC article.

2

Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer.

Merry CR, McMahon S, Forrest ME, Bartels CF, Saiakhova A, Bartel CA, Scacheri PC, Thompson CL, Jackson MW, Harris LN, Khalil AM. Merry CR, et al. Among authors: saiakhova a. Oncotarget. 2016 Aug 16;7(33):53230-53244. doi: 10.18632/oncotarget.10637. Oncotarget. 2016. PMID: 27449296 Free PMC article.

3

Epigenomic enhancer profiling defines a signature of colon cancer.

Akhtar-Zaidi B, Cowper-Sal-lari R, Corradin O, Saiakhova A, Bartels CF, Balasubramanian D, Myeroff L, Lutterbaugh J, Jarrar A, Kalady MF, Willis J, Moore JH, Tesar PJ, Laframboise T, Markowitz S, Lupien M, Scacheri PC. Akhtar-Zaidi B, et al. Among authors: saiakhova a. Science. 2012 May 11;336(6082):736-9. doi: 10.1126/science.1217277. Epub 2012 Apr 12. Science. 2012. PMID: 22499810 Free PMC article.

4

Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome.

Cohen AJ, Saiakhova A, Corradin O, Luppino JM, Lovrenert K, Bartels CF, Morrow JJ, Mack SC, Dhillon G, Beard L, Myeroff L, Kalady MF, Willis J, Bradner JE, Keri RA, Berger NA, Pruett-Miller SM, Markowitz SD, Scacheri PC. Cohen AJ, et al. Among authors: saiakhova a. Nat Commun. 2017 Feb 7;8:14400. doi: 10.1038/ncomms14400. Nat Commun. 2017. PMID: 28169291 Free PMC article.

5

Mismatch repair-signature mutations activate gene enhancers across human colorectal cancer epigenomes.

Hung S, Saiakhova A, Faber ZJ, Bartels CF, Neu D, Bayles I, Ojo E, Hong ES, Pontius WD, Morton AR, Liu R, Kalady MF, Wald DN, Markowitz S, Scacheri PC. Hung S, et al. Among authors: saiakhova a. Elife. 2019 Feb 13;8:e40760. doi: 10.7554/eLife.40760. Elife. 2019. PMID: 30759065 Free PMC article.

6

CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression.

Yao H, Hannum DF, Zhai Y, Hill SF, Albanus RD', Lou W, Skidmore JM, Sanchez G, Saiakhova A, Bielas SL, Scacheri P, Ljungman M, Parker SCJ, Martin DM. Yao H, et al. Among authors: saiakhova a. Sci Rep. 2020 Oct 15;10(1):17445. doi: 10.1038/s41598-020-74537-4. Sci Rep. 2020. PMID: 33060836 Free PMC article.

7

Integrative genomic analysis of human ribosomal DNA.

Zentner GE, Saiakhova A, Manaenkov P, Adams MD, Scacheri PC. Zentner GE, et al. Among authors: saiakhova a. Nucleic Acids Res. 2011 Jul;39(12):4949-60. doi: 10.1093/nar/gkq1326. Epub 2011 Feb 25. Nucleic Acids Res. 2011. PMID: 21355038 Free PMC article.

8

Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits.

Corradin O, Saiakhova A, Akhtar-Zaidi B, Myeroff L, Willis J, Cowper-Sal lari R, Lupien M, Markowitz S, Scacheri PC. Corradin O, et al. Among authors: saiakhova a. Genome Res. 2014 Jan;24(1):1-13. doi: 10.1101/gr.164079.113. Epub 2013 Nov 6. Genome Res. 2014. PMID: 24196873 Free PMC article.

9

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.

Morrow JJ, Bayles I, Funnell APW, Miller TE, Saiakhova A, Lizardo MM, Bartels CF, Kapteijn MY, Hung S, Mendoza A, Dhillon G, Chee DR, Myers JT, Allen F, Gambarotti M, Righi A, DiFeo A, Rubin BP, Huang AY, Meltzer PS, Helman LJ, Picci P, Versteeg HH, Stamatoyannopoulos JA, Khanna C, Scacheri PC. Morrow JJ, et al. Among authors: saiakhova a. Nat Med. 2018 Feb;24(2):176-185. doi: 10.1038/nm.4475. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334376 Free PMC article.

10

Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma.

Bayles I, Krajewska M, Pontius WD, Saiakhova A, Morrow JJ, Bartels C, Lu J, Faber ZJ, Fedorov Y, Hong ES, Karnuta JM, Rubin B, Adams DJ, George RE, Scacheri PC. Bayles I, et al. Among authors: saiakhova a. J Clin Invest. 2019 Oct 1;129(10):4377-4392. doi: 10.1172/JCI127718. J Clin Invest. 2019. PMID: 31498151 Free PMC article.

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