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114 results

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CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms.
Li XY, Das I, Lepletier A, Addala V, Bald T, Stannard K, Barkauskas D, Liu J, Aguilera AR, Takeda K, Braun M, Nakamura K, Jacquelin S, Lane SW, Teng MW, Dougall WC, Smyth MJ. Li XY, et al. Among authors: lane sw. J Clin Invest. 2018 Jun 1;128(6):2613-2625. doi: 10.1172/JCI98769. Epub 2018 May 14. J Clin Invest. 2018. PMID: 29757192 Free PMC article. Retracted.
Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.
Gartlan KH, Markey KA, Varelias A, Bunting MD, Koyama M, Kuns RD, Raffelt NC, Olver SD, Lineburg KE, Cheong M, Teal BE, Lor M, Comerford I, Teng MW, Smyth MJ, McCluskey J, Rossjohn J, Stockinger B, Boyle GM, Lane SW, Clouston AD, McColl SR, MacDonald KP, Hill GR. Gartlan KH, et al. Among authors: lane sw. Blood. 2015 Sep 24;126(13):1609-20. doi: 10.1182/blood-2015-01-622662. Epub 2015 Jul 23. Blood. 2015. PMID: 26206951 Free article.
Harnessing the immune system in acute myeloid leukaemia.
Austin R, Smyth MJ, Lane SW. Austin R, et al. Among authors: lane sw. Crit Rev Oncol Hematol. 2016 Jul;103:62-77. doi: 10.1016/j.critrevonc.2016.04.020. Epub 2016 May 11. Crit Rev Oncol Hematol. 2016. PMID: 27247119 Review.
Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.
Le Texier L, Lineburg KE, Cao B, McDonald-Hyman C, Leveque-El Mouttie L, Nicholls J, Melino M, Nalkurthi BC, Alexander KA, Teal B, Blake SJ, Souza-Fonseca-Guimaraes F, Engwerda CR, Kuns RD, Lane SW, Teng M, Teh C, Gray D, Clouston AD, Nilsson SK, Blazar BR, Hill GR, MacDonald KP. Le Texier L, et al. Among authors: lane sw. JCI Insight. 2016 Sep 22;1(15):e86850. doi: 10.1172/jci.insight.86850. JCI Insight. 2016. PMID: 27699243 Free PMC article.
GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.
Bunting MD, Varelias A, Souza-Fonseca-Guimaraes F, Schuster IS, Lineburg KE, Kuns RD, Fleming P, Locke KR, Huntington ND, Blazar BR, Lane SW, Tey SK, MacDonald KP, Smyth MJ, Degli-Esposti MA, Hill GR. Bunting MD, et al. Among authors: lane sw. Blood. 2017 Feb 2;129(5):630-642. doi: 10.1182/blood-2016-08-734020. Epub 2016 Dec 7. Blood. 2017. PMID: 27927647 Free PMC article.
Acute myeloid leukemia stem cell function is preserved in the absence of autophagy.
Porter AH, Leveque-El Mouttie L, Vu T, Bruedigam C, Sutton J, Jacquelin S, Hill GR, MacDonald KPA, Lane SW. Porter AH, et al. Among authors: lane sw. Haematologica. 2017 Sep;102(9):e344-e347. doi: 10.3324/haematol.2017.166389. Epub 2017 May 26. Haematologica. 2017. PMID: 28550181 Free PMC article. No abstract available.
Flt-3L Expansion of Recipient CD8α+ Dendritic Cells Deletes Alloreactive Donor T Cells and Represents an Alternative to Posttransplant Cyclophosphamide for the Prevention of GVHD.
Markey KA, Kuns RD, Browne DJ, Gartlan KH, Robb RJ, Martins JP, Henden AS, Minnie SA, Cheong M, Koyama M, Smyth MJ, Steptoe RJ, Belz GT, Brocker T, Degli-Esposti MA, Lane SW, Hill GR. Markey KA, et al. Among authors: lane sw. Clin Cancer Res. 2018 Apr 1;24(7):1604-1616. doi: 10.1158/1078-0432.CCR-17-2148. Epub 2018 Jan 24. Clin Cancer Res. 2018. PMID: 29367429
Recipient mucosal-associated invariant T cells control GVHD within the colon.
Varelias A, Bunting MD, Ormerod KL, Koyama M, Olver SD, Straube J, Kuns RD, Robb RJ, Henden AS, Cooper L, Lachner N, Gartlan KH, Lantz O, Kjer-Nielsen L, Mak JY, Fairlie DP, Clouston AD, McCluskey J, Rossjohn J, Lane SW, Hugenholtz P, Hill GR. Varelias A, et al. Among authors: lane sw. J Clin Invest. 2018 May 1;128(5):1919-1936. doi: 10.1172/JCI91646. Epub 2018 Apr 9. J Clin Invest. 2018. PMID: 29629900 Free PMC article.
114 results