Morgan RG - Search Results

1

Optimized delivery of siRNA into 3D tumor spheroid cultures in situ.

Morgan RG, Chambers AC, Legge DN, Coles SJ, Greenhough A, Williams AC. Morgan RG, et al. Sci Rep. 2018 May 21;8(1):7952. doi: 10.1038/s41598-018-26253-3. Sci Rep. 2018. PMID: 29785035 Free PMC article.

2

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.

Morgan RG, Molnár E, Jones RF, Collard TJ, Lane JD, Greenhough A, Paraskeva C, Williams AC. Morgan RG, et al. Br J Cancer. 2015 Feb 17;112(4):714-9. doi: 10.1038/bjc.2015.4. Epub 2015 Jan 22. Br J Cancer. 2015. PMID: 25611300 Free PMC article.

3

LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity.

Morgan RG, Mortensson E, Legge DN, Gupta B, Collard TJ, Greenhough A, Williams AC. Morgan RG, et al. Br J Cancer. 2018 Feb 20;118(4):558-565. doi: 10.1038/bjc.2017.412. Epub 2017 Nov 16. Br J Cancer. 2018. PMID: 29149105 Free PMC article.

4

Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic?

Morgan RG, Mortensson E, Williams AC. Morgan RG, et al. Br J Cancer. 2018 May;118(11):1410-1418. doi: 10.1038/s41416-018-0118-6. Epub 2018 May 30. Br J Cancer. 2018. PMID: 29844449 Free PMC article. Review.

5

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells.

Morgan RG, Ridsdale J, Payne M, Heesom KJ, Wilson MC, Davidson A, Greenhough A, Davies S, Williams AC, Blair A, Waterman ML, Tonks A, Darley RL. Morgan RG, et al. Haematologica. 2019 Jul;104(7):1365-1377. doi: 10.3324/haematol.2018.202846. Epub 2019 Jan 10. Haematologica. 2019. PMID: 30630973 Free PMC article.

6

BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination.

Parker C, Chambers AC, Flanagan DJ, Ho JWY, Collard TJ, Ngo G, Baird DM, Timms P, Morgan RG, Sansom OJ, Williams AC. Parker C, et al. Among authors: morgan rg. DNA Repair (Amst). 2022 Jul;115:103331. doi: 10.1016/j.dnarep.2022.103331. Epub 2022 Apr 16. DNA Repair (Amst). 2022. PMID: 35468497 Free PMC article.

7

Using Flow Cytometry to Detect and Measure Intracellular Thiol Redox Status in Viable T Cells from Heterogeneous Populations.

Wadley AJ, Morgan RG, Darley RL, Hole PS, Coles SJ. Wadley AJ, et al. Among authors: morgan rg. Methods Mol Biol. 2019;1990:53-70. doi: 10.1007/978-1-4939-9463-2_5. Methods Mol Biol. 2019. PMID: 31148062

8

Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers.

Wadley AJ, Morgan RG, Heesom KJ, Hole PS, Coles SJ. Wadley AJ, et al. Among authors: morgan rg. MethodsX. 2018 Nov 1;5:1473-1483. doi: 10.1016/j.mex.2018.10.013. eCollection 2018. MethodsX. 2018. PMID: 30505701 Free PMC article.

9

Preliminary evidence of reductive stress in human cytotoxic T cells following exercise.

Wadley AJ, Holliday A, Morgan RG, Heesom KJ, Aldred S, Peters DM, Bueno AA, Coles SJ. Wadley AJ, et al. Among authors: morgan rg. J Appl Physiol (1985). 2018 Aug 1;125(2):586-595. doi: 10.1152/japplphysiol.01137.2017. Epub 2018 Apr 12. J Appl Physiol (1985). 2018. PMID: 29648517 Free article.

10

Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells.

Menendez-Gonzalez JB, Sinnadurai S, Gibbs A, Thomas LA, Konstantinou M, Garcia-Valverde A, Boyer M, Wang Z, Boyd AS, Blair A, Morgan RG, Rodrigues NP. Menendez-Gonzalez JB, et al. Among authors: morgan rg. Sci Rep. 2019 Aug 21;9(1):12212. doi: 10.1038/s41598-019-48589-0. Sci Rep. 2019. PMID: 31434974 Free PMC article.

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