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Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase.
Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6195-6200. doi: 10.1073/pnas.1720298115. Epub 2018 May 25.
Proc Natl Acad Sci U S A. 2018.
PMID: 29802230
Free PMC article.
Stepwise nitrosylation of the nonheme iron site in an engineered azurin and a molecular basis for nitric oxide signaling mediated by nonheme iron proteins.
Tian S, Fan R, Albert T, Khade RL, Dai H, Harnden KA, Hosseinzadeh P, Liu J, Nilges MJ, Zhang Y, Moënne-Loccoz P, Guo Y, Lu Y.
Tian S, et al. Among authors: harnden ka.
Chem Sci. 2021 Mar 31;12(19):6569-6579. doi: 10.1039/d1sc00364j.
Chem Sci. 2021.
PMID: 34040732
Free PMC article.
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Overview of Methods for Purification and Characterization of Metalloproteins.
Harnden KA, Roy A, Hosseinzadeh P.
Harnden KA, et al.
Curr Protoc. 2021 Aug;1(8):e234. doi: 10.1002/cpz1.234.
Curr Protoc. 2021.
PMID: 34436821
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A designed Copper Histidine-brace enzyme for oxidative depolymerization of polysaccharides as a model of lytic polysaccharide monooxygenase.
Liu Y, Harnden KA, Van Stappen C, Dikanov SA, Lu Y.
Liu Y, et al. Among authors: harnden ka.
Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2308286120. doi: 10.1073/pnas.2308286120. Epub 2023 Oct 16.
Proc Natl Acad Sci U S A. 2023.
PMID: 37844252
Free PMC article.
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A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harnden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA.
Sparks RP, et al. Among authors: harnden ka.
J Biol Chem. 2019 Nov 15;294(46):17168-17185. doi: 10.1074/jbc.RA119.008865. Epub 2019 Sep 12.
J Biol Chem. 2019.
PMID: 31515268
Free PMC article.
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Correction: A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion.
Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harnden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA.
Sparks RP, et al. Among authors: harnden ka.
J Biol Chem. 2022 Nov;298(11):102576. doi: 10.1016/j.jbc.2022.102576. Epub 2022 Oct 15.
J Biol Chem. 2022.
PMID: 36257250
Free PMC article.
No abstract available.
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