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CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.
György B, Lööv C, Zaborowski MP, Takeda S, Kleinstiver BP, Commins C, Kastanenka K, Mu D, Volak A, Giedraitis V, Lannfelt L, Maguire CA, Joung JK, Hyman BT, Breakefield XO, Ingelsson M. György B, et al. Among authors: lannfelt l. Mol Ther Nucleic Acids. 2018 Jun 1;11:429-440. doi: 10.1016/j.omtn.2018.03.007. Epub 2018 Mar 16. Mol Ther Nucleic Acids. 2018. PMID: 29858078 Free PMC article.
No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain.
Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, Standaert DG, Irizarry MC, Hyman BT. Ingelsson M, et al. Among authors: lannfelt l. Acta Neuropathol. 2006 Oct;112(4):439-49. doi: 10.1007/s00401-006-0095-3. Epub 2006 Jun 27. Acta Neuropathol. 2006. PMID: 16802167
New Alzheimer's disease locus on chromosome 8.
Giedraitis V, Hedlund M, Skoglund L, Blom E, Ingvast S, Brundin R, Lannfelt L, Glaser A. Giedraitis V, et al. Among authors: lannfelt l. J Med Genet. 2006 Dec;43(12):931-5. doi: 10.1136/jmg.2006.043000. Epub 2006 Jul 6. J Med Genet. 2006. PMID: 16825432 Free PMC article.
The tau S305S mutation causes frontotemporal dementia with parkinsonism.
Skoglund L, Viitanen M, Kalimo H, Lannfelt L, Jönhagen ME, Ingelsson M, Glaser A, Herva R. Skoglund L, et al. Among authors: lannfelt l. Eur J Neurol. 2008 Feb;15(2):156-61. doi: 10.1111/j.1468-1331.2007.02017.x. Epub 2007 Dec 18. Eur J Neurol. 2008. PMID: 18093153
405 results