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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.
Gogola E, Duarte AA, de Ruiter JR, Wiegant WW, Schmid JA, de Bruijn R, James DI, Guerrero Llobet S, Vis DJ, Annunziato S, van den Broek B, Barazas M, Kersbergen A, van de Ven M, Tarsounas M, Ogilvie DJ, van Vugt M, Wessels LFA, Bartkova J, Gromova I, Andújar-Sánchez M, Bartek J, Lopes M, van Attikum H, Borst P, Jonkers J, Rottenberg S. Gogola E, et al. Among authors: van de ven m, van den broek b, van vugt m, van attikum h. Cancer Cell. 2018 Jun 11;33(6):1078-1093.e12. doi: 10.1016/j.ccell.2018.05.008. Cancer Cell. 2018. PMID: 29894693 Free article.
EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells.
van de Kooij B, Schreuder A, Pavani RS, Garzero V, Van Hoeck A, San Martin Alonso M, Koerse D, Wendel TJ, Callen E, Boom J, Mei H, Cuppen E, Nussenzweig A, van Attikum H, Noordermeer SM. van de Kooij B, et al. Among authors: van attikum h. bioRxiv [Preprint]. 2023 Feb 24:2023.02.24.529205. doi: 10.1101/2023.02.24.529205. bioRxiv. 2023. PMID: 37720033 Free PMC article. Preprint.
DDB2 promotes chromatin decondensation at UV-induced DNA damage.
Luijsterburg MS, Lindh M, Acs K, Vrouwe MG, Pines A, van Attikum H, Mullenders LH, Dantuma NP. Luijsterburg MS, et al. Among authors: van attikum h. J Cell Biol. 2012 Apr 16;197(2):267-81. doi: 10.1083/jcb.201106074. Epub 2012 Apr 9. J Cell Biol. 2012. PMID: 22492724 Free PMC article.
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection.
Costelloe T, Louge R, Tomimatsu N, Mukherjee B, Martini E, Khadaroo B, Dubois K, Wiegant WW, Thierry A, Burma S, van Attikum H, Llorente B. Costelloe T, et al. Among authors: van attikum h. Nature. 2012 Sep 27;489(7417):581-4. doi: 10.1038/nature11353. Epub 2012 Sep 9. Nature. 2012. PMID: 22960744 Free PMC article.
The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.
Typas D, Luijsterburg MS, Wiegant WW, Diakatou M, Helfricht A, Thijssen PE, van den Broek B, Mullenders LH, van Attikum H. Typas D, et al. Among authors: van den broek b, van attikum h. Nucleic Acids Res. 2016 Apr 7;44(6):2976. doi: 10.1093/nar/gkv1480. Epub 2015 Dec 15. Nucleic Acids Res. 2016. PMID: 26673702 Free PMC article. No abstract available.
95 results