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Motivational valence is determined by striatal melanocortin 4 receptors.
Klawonn AM, Fritz M, Nilsson A, Bonaventura J, Shionoya K, Mirrasekhian E, Karlsson U, Jaarola M, Granseth B, Blomqvist A, Michaelides M, Engblom D. Klawonn AM, et al. Among authors: shionoya k. J Clin Invest. 2018 Jul 2;128(7):3160-3170. doi: 10.1172/JCI97854. Epub 2018 Jun 18. J Clin Invest. 2018. PMID: 29911992 Free PMC article.
The antipyretic effect of paracetamol occurs independent of transient receptor potential ankyrin 1-mediated hypothermia and is associated with prostaglandin inhibition in the brain.
Mirrasekhian E, Nilsson JLÅ, Shionoya K, Blomgren A, Zygmunt PM, Engblom D, Högestätt ED, Blomqvist A. Mirrasekhian E, et al. Among authors: shionoya k. FASEB J. 2018 Oct;32(10):5751-5759. doi: 10.1096/fj.201800272R. Epub 2018 May 8. FASEB J. 2018. PMID: 29738273 Free article.
We conclude that paracetamol's antipyretic effect in mice is dependent on inhibition of cyclooxygenase activity, including the formation of pyrogenic prostaglandin E(2), whereas paracetamol-induced hypothermia likely is mediated by the activation of TRPA1 by electrophilic metabol …
We conclude that paracetamol's antipyretic effect in mice is dependent on inhibition of cyclooxygenase activity, including the formation of …
NF-κB signaling in tanycytes mediates inflammation-induced anorexia.
Böttcher M, Müller-Fielitz H, Sundaram SM, Gallet S, Neve V, Shionoya K, Zager A, Quan N, Liu X, Schmidt-Ullrich R, Haenold R, Wenzel J, Blomqvist A, Engblom D, Prevot V, Schwaninger M. Böttcher M, et al. Among authors: shionoya k. Mol Metab. 2020 Sep;39:101022. doi: 10.1016/j.molmet.2020.101022. Epub 2020 May 21. Mol Metab. 2020. PMID: 32446877 Free PMC article.
89 results