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New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors.
Byrne DP, Li Y, Ramakrishnan K, Barsukov IL, Yates EA, Eyers CE, Papy-Garcia D, Chantepie S, Pagadala V, Liu J, Wells C, Drewry DH, Zuercher WJ, Berry NG, Fernig DG, Eyers PA. Byrne DP, et al. Among authors: eyers pa, eyers ce. Biochem J. 2018 Aug 14;475(15):2417-2433. doi: 10.1042/BCJ20180265. Biochem J. 2018. PMID: 29934491 Free PMC article.
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.
Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. Murphy JM, et al. Among authors: eyers pa. Biochem J. 2014 Jan 15;457(2):323-34. doi: 10.1042/BJ20131174. Biochem J. 2014. PMID: 24107129 Free PMC article.
Going for broke: targeting the human cancer pseudokinome.
Bailey FP, Byrne DP, McSkimming D, Kannan N, Eyers PA. Bailey FP, et al. Among authors: eyers pa. Biochem J. 2015 Jan 15;465(2):195-211. doi: 10.1042/BJ20141060. Biochem J. 2015. PMID: 25559089 Review.
2) Going for broke: targeting the human cancer pseudokinome.
Bailey FP, Byrne DP, McSkimming D, Kannan N, Eyers PA. Bailey FP, et al. Among authors: eyers pa. Biochem J. 2015 Feb 15;466(1):201. doi: 10.1042/bj4660201v. Biochem J. 2015. PMID: 25656056 No abstract available.
Human CDK18 promotes replication stress signaling and genome stability.
Barone G, Staples CJ, Ganesh A, Patterson KW, Bryne DP, Myers KN, Patil AA, Eyers CE, Maslen S, Skehel JM, Eyers PA, Collis SJ. Barone G, et al. Among authors: eyers pa, eyers ce. Nucleic Acids Res. 2016 Oct 14;44(18):8772-8785. doi: 10.1093/nar/gkw615. Epub 2016 Jul 5. Nucleic Acids Res. 2016. PMID: 27382066 Free PMC article.
109 results