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iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling.
Moreno CL, Della Guardia L, Shnyder V, Ortiz-Virumbrales M, Kruglikov I, Zhang B, Schadt EE, Tanzi RE, Noggle S, Buettner C, Gandy S. Moreno CL, et al. Among authors: ortiz virumbrales m. Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5. Mol Neurodegener. 2018. PMID: 29945658 Free PMC article.
CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.
Ortiz-Virumbrales M, Moreno CL, Kruglikov I, Marazuela P, Sproul A, Jacob S, Zimmer M, Paull D, Zhang B, Schadt EE, Ehrlich ME, Tanzi RE, Arancio O, Noggle S, Gandy S. Ortiz-Virumbrales M, et al. Acta Neuropathol Commun. 2017 Oct 27;5(1):77. doi: 10.1186/s40478-017-0475-z. Acta Neuropathol Commun. 2017. PMID: 29078805 Free PMC article.
Mesenchymal Stromal Cell Derived Membrane Particles Are Internalized by Macrophages and Endothelial Cells Through Receptor-Mediated Endocytosis and Phagocytosis.
da Costa Gonçalves F, Korevaar SS, Ortiz Virumbrales M, Baan CC, Reinders MEJ, Merino A, Lombardo E, Hoogduijn MJ. da Costa Gonçalves F, et al. Among authors: ortiz virumbrales m. Front Immunol. 2021 Mar 15;12:651109. doi: 10.3389/fimmu.2021.651109. eCollection 2021. Front Immunol. 2021. PMID: 33790914 Free PMC article.
Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2.
Ortiz-Virumbrales M, Menta R, Pérez LM, Lucchesi O, Mancheño-Corvo P, Avivar-Valderas Á, Palacios I, Herrero-Mendez A, Dalemans W, de la Rosa O, Lombardo E. Ortiz-Virumbrales M, et al. Stem Cell Res Ther. 2020 Nov 2;11(1):462. doi: 10.1186/s13287-020-01975-2. Stem Cell Res Ther. 2020. PMID: 33138862 Free PMC article.
Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients.
Avivar-Valderas A, Martín-Martín C, Ramírez C, Del Río B, Menta R, Mancheño-Corvo P, Ortiz-Virumbrales M, Herrero-Méndez Á, Panés J, García-Olmo D, Castañer JL, Palacios I, Lombardo E, Dalemans W, DelaRosa O. Avivar-Valderas A, et al. Among authors: ortiz virumbrales m. Front Immunol. 2019 Jun 14;10:1244. doi: 10.3389/fimmu.2019.01244. eCollection 2019. Front Immunol. 2019. PMID: 31258526 Free PMC article.