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TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.
Cheung SY, Henrot M, Al-Saad M, Baumann M, Muller H, Unger A, Rubaiy HN, Mathar I, Dinkel K, Nussbaumer P, Klebl B, Freichel M, Rode B, Trainor S, Clapcote SJ, Christmann M, Waldmann H, Abbas SK, Beech DJ, Vasudev NS. Cheung SY, et al. Among authors: mathar i. Oncotarget. 2018 Jul 3;9(51):29634-29643. doi: 10.18632/oncotarget.25659. eCollection 2018 Jul 3. Oncotarget. 2018. PMID: 30038709 Free PMC article.
Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.
Bröker-Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, Guzman R, Schwarz Y, Lai A, Weißgerber P, Schwegler H, Dietrich A, Both M, Sprengel R, Draguhn A, Köhr G, Fakler B, Flockerzi V, Bruns D, Freichel M. Bröker-Lai J, et al. Among authors: mathar i. EMBO J. 2017 Sep 15;36(18):2770-2789. doi: 10.15252/embj.201696369. Epub 2017 Aug 8. EMBO J. 2017. PMID: 28790178 Free PMC article.
Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.
Mathar I, Vennekens R, Meissner M, Kees F, Van der Mieren G, Camacho Londoño JE, Uhl S, Voets T, Hummel B, van den Bergh A, Herijgers P, Nilius B, Flockerzi V, Schweda F, Freichel M. Mathar I, et al. J Clin Invest. 2010 Sep;120(9):3267-79. doi: 10.1172/JCI41348. Epub 2010 Aug 2. J Clin Invest. 2010. PMID: 20679729 Free PMC article.
Increased β-adrenergic inotropy in ventricular myocardium from Trpm4-/- mice.
Mathar I, Kecskes M, Van der Mieren G, Jacobs G, Camacho Londoño JE, Uhl S, Flockerzi V, Voets T, Freichel M, Nilius B, Herijgers P, Vennekens R. Mathar I, et al. Circ Res. 2014 Jan 17;114(2):283-94. doi: 10.1161/CIRCRESAHA.114.302835. Epub 2013 Nov 13. Circ Res. 2014. PMID: 24226423
26 results