Mucke L - Search Results

1

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.

Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ. Willsey AJ, et al. Among authors: mucke l. Cell. 2018 Jul 26;174(3):505-520. doi: 10.1016/j.cell.2018.06.016. Cell. 2018. PMID: 30053424 Free PMC article. Review.

2

Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis.

Xu X, Yang D, Wyss-Coray T, Yan J, Gan L, Sun Y, Mucke L. Xu X, et al. Among authors: mucke l. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7547-52. doi: 10.1073/pnas.96.13.7547. Proc Natl Acad Sci U S A. 1999. PMID: 10377452 Free PMC article.

3

Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.

Esposito L, Gan L, Yu GQ, Essrich C, Mucke L. Esposito L, et al. Among authors: mucke l. J Neurochem. 2004 Dec;91(6):1260-74. doi: 10.1111/j.1471-4159.2004.02816.x. J Neurochem. 2004. PMID: 15584903 Free article.

4

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.

Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S, Mucke L, Gan L. Chen J, et al. Among authors: mucke l. J Biol Chem. 2005 Dec 2;280(48):40364-74. doi: 10.1074/jbc.M509329200. Epub 2005 Sep 23. J Biol Chem. 2005. PMID: 16183991 Free article.

5

Paths of convergence: sirtuins in aging and neurodegeneration.

Gan L, Mucke L. Gan L, et al. Among authors: mucke l. Neuron. 2008 Apr 10;58(1):10-4. doi: 10.1016/j.neuron.2008.03.015. Neuron. 2008. PMID: 18400158 Free PMC article. Review.

6

Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease.

Sun B, Halabisky B, Zhou Y, Palop JJ, Yu G, Mucke L, Gan L. Sun B, et al. Among authors: mucke l. Cell Stem Cell. 2009 Dec 4;5(6):624-33. doi: 10.1016/j.stem.2009.10.003. Cell Stem Cell. 2009. PMID: 19951690 Free PMC article.

7

Tau reduction prevents Abeta-induced defects in axonal transport.

Vossel KA, Zhang K, Brodbeck J, Daub AC, Sharma P, Finkbeiner S, Cui B, Mucke L. Vossel KA, et al. Among authors: mucke l. Science. 2010 Oct 8;330(6001):198. doi: 10.1126/science.1194653. Epub 2010 Sep 9. Science. 2010. PMID: 20829454 Free PMC article.

8

Selective targeting of microglia by quantum dots.

Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L. Minami SS, et al. Among authors: mucke l. J Neuroinflammation. 2012 Jan 24;9:22. doi: 10.1186/1742-2094-9-22. J Neuroinflammation. 2012. PMID: 22272874 Free PMC article.

9

Alzheimer mechanisms and therapeutic strategies.

Huang Y, Mucke L. Huang Y, et al. Among authors: mucke l. Cell. 2012 Mar 16;148(6):1204-22. doi: 10.1016/j.cell.2012.02.040. Cell. 2012. PMID: 22424230 Free PMC article. Review.

10

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.

Minami SS, Min SW, Krabbe G, Wang C, Zhou Y, Asgarov R, Li Y, Martens LH, Elia LP, Ward ME, Mucke L, Farese RV Jr, Gan L. Minami SS, et al. Among authors: mucke l. Nat Med. 2014 Oct;20(10):1157-64. doi: 10.1038/nm.3672. Epub 2014 Sep 28. Nat Med. 2014. PMID: 25261995 Free PMC article.

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