Harraz OF - Search Results

1

PIP₂ depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells.

Harraz OF, Longden TA, Hill-Eubanks D, Nelson MT. Harraz OF, et al. Elife. 2018 Aug 7;7:e38689. doi: 10.7554/eLife.38689. Elife. 2018. PMID: 30084828 Free PMC article.

2

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP₂ depletion.

Harraz OF, Longden TA, Dabertrand F, Hill-Eubanks D, Nelson MT. Harraz OF, et al. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3569-E3577. doi: 10.1073/pnas.1800201115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581272 Free PMC article.

3

TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw.

Gomes CC, Gayden T, Bajic A, Harraz OF, Pratt J, Nikbakht H, Bareke E, Diniz MG, Castro WH, St-Onge P, Sinnett D, Han H, Rivera B, Mikael LG, De Jay N, Kleinman CL, Valera ET, Bassenden AV, Berghuis AM, Majewski J, Nelson MT, Gomez RS, Jabado N. Gomes CC, et al. Among authors: harraz of. Nat Commun. 2018 Nov 1;9(1):4572. doi: 10.1038/s41467-018-06690-4. Nat Commun. 2018. PMID: 30385747 Free PMC article.

4

The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K⁺-mediated neurovascular communication.

Moshkforoush A, Ashenagar B, Harraz OF, Dabertrand F, Longden TA, Nelson MT, Tsoukias NM. Moshkforoush A, et al. Among authors: harraz of. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16626-16637. doi: 10.1073/pnas.2000151117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601236 Free PMC article.

5

PIP₂: A critical regulator of vascular ion channels hiding in plain sight.

Harraz OF, Hill-Eubanks D, Nelson MT. Harraz OF, et al. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20378-20389. doi: 10.1073/pnas.2006737117. Epub 2020 Aug 6. Proc Natl Acad Sci U S A. 2020. PMID: 32764146 Free PMC article. Review.

6

PIP₂ Improves Cerebral Blood Flow in a Mouse Model of Alzheimer's Disease.

Mughal A, Harraz OF, Gonzales AL, Hill-Eubanks D, Nelson MT. Mughal A, et al. Among authors: harraz of. Function (Oxf). 2021 Feb 22;2(2):zqab010. doi: 10.1093/function/zqab010. eCollection 2021. Function (Oxf). 2021. PMID: 33763649 Free PMC article.

7

PIP₂ corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity.

Dabertrand F, Harraz OF, Koide M, Longden TA, Rosehart AC, Hill-Eubanks DC, Joutel A, Nelson MT. Dabertrand F, et al. Among authors: harraz of. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2025998118. doi: 10.1073/pnas.2025998118. Proc Natl Acad Sci U S A. 2021. PMID: 33875602 Free PMC article.

8

Zinc drives vasorelaxation by acting in sensory nerves, endothelium and smooth muscle.

Betrie AH, Brock JA, Harraz OF, Bush AI, He GW, Nelson MT, Angus JA, Wright CE, Ayton S. Betrie AH, et al. Among authors: harraz of. Nat Commun. 2021 Jun 1;12(1):3296. doi: 10.1038/s41467-021-23198-6. Nat Commun. 2021. PMID: 34075043 Free PMC article.

9

Local IP₃ receptor-mediated Ca²⁺ signals compound to direct blood flow in brain capillaries.

Longden TA, Mughal A, Hennig GW, Harraz OF, Shui B, Lee FK, Lee JC, Reining S, Kotlikoff MI, König GM, Kostenis E, Hill-Eubanks D, Nelson MT. Longden TA, et al. Among authors: harraz of. Sci Adv. 2021 Jul 21;7(30):eabh0101. doi: 10.1126/sciadv.abh0101. Print 2021 Jul. Sci Adv. 2021. PMID: 34290098 Free PMC article.

10

Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease.

Koide M, Harraz OF, Dabertrand F, Longden TA, Ferris HR, Wellman GC, Hill-Eubanks DC, Greenstein AS, Nelson MT. Koide M, et al. Among authors: harraz of. J Clin Invest. 2021 Sep 15;131(18):e149029. doi: 10.1172/JCI149029. J Clin Invest. 2021. PMID: 34351870 Free PMC article.

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