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Nutrient scavenging in cancer.
Finicle BT, Jayashankar V, Edinger AL. Finicle BT, et al. Among authors: edinger al. Nat Rev Cancer. 2018 Oct;18(10):619-633. doi: 10.1038/s41568-018-0048-x. Nat Rev Cancer. 2018. PMID: 30097614 Review.
Nutrient transporters: the Achilles' heel of anabolism.
McCracken AN, Edinger AL. McCracken AN, et al. Among authors: edinger al. Trends Endocrinol Metab. 2013 Apr;24(4):200-8. doi: 10.1016/j.tem.2013.01.002. Epub 2013 Feb 8. Trends Endocrinol Metab. 2013. PMID: 23402769 Free PMC article. Review.
Loss of TSC2 confers resistance to ceramide and nutrient deprivation.
Guenther GG, Liu G, Ramirez MU, McMonigle RJ, Kim SM, McCracken AN, Joo Y, Ushach I, Nguyen NL, Edinger AL. Guenther GG, et al. Among authors: edinger al. Oncogene. 2014 Apr 3;33(14):1776-87. doi: 10.1038/onc.2013.139. Epub 2013 Apr 22. Oncogene. 2014. PMID: 23604129 Free PMC article.
Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo.
Chen B, Roy SG, McMonigle RJ, Keebaugh A, McCracken AN, Selwan E, Fransson R, Fallegger D, Huwiler A, Kleinman MT, Edinger AL, Hanessian S. Chen B, et al. Among authors: edinger al. ACS Chem Biol. 2016 Feb 19;11(2):409-14. doi: 10.1021/acschembio.5b00761. Epub 2015 Dec 14. ACS Chem Biol. 2016. PMID: 26653336 Free PMC article.
Attacking the supply wagons to starve cancer cells to death.
Selwan EM, Finicle BT, Kim SM, Edinger AL. Selwan EM, et al. Among authors: edinger al. FEBS Lett. 2016 Apr;590(7):885-907. doi: 10.1002/1873-3468.12121. Epub 2016 Mar 22. FEBS Lett. 2016. PMID: 26938658 Free PMC article. Review.
73 results