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Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growth.
Thijssen VL, Paulis YW, Nowak-Sliwinska P, Deumelandt KL, Hosaka K, Soetekouw PM, Cimpean AM, Raica M, Pauwels P, van den Oord JJ, Tjan-Heijnen VC, Hendrix MJ, Heldin CH, Cao Y, Griffioen AW. Thijssen VL, et al. Among authors: deumelandt kl. J Pathol. 2018 Dec;246(4):447-458. doi: 10.1002/path.5152. Epub 2018 Oct 30. J Pathol. 2018. PMID: 30101525 Free PMC article.
Tweety-Homolog 1 Drives Brain Colonization of Gliomas.
Jung E, Osswald M, Blaes J, Wiestler B, Sahm F, Schmenger T, Solecki G, Deumelandt K, Kurz FT, Xie R, Weil S, Heil O, Thomé C, Gömmel M, Syed M, Häring P, Huber PE, Heiland S, Platten M, von Deimling A, Wick W, Winkler F. Jung E, et al. J Neurosci. 2017 Jul 19;37(29):6837-6850. doi: 10.1523/JNEUROSCI.3532-16.2017. Epub 2017 Jun 12. J Neurosci. 2017. PMID: 28607172 Free PMC article.
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
Bunse L, Pusch S, Bunse T, Sahm F, Sanghvi K, Friedrich M, Alansary D, Sonner JK, Green E, Deumelandt K, Kilian M, Neftel C, Uhlig S, Kessler T, von Landenberg A, Berghoff AS, Marsh K, Steadman M, Zhu D, Nicolay B, Wiestler B, Breckwoldt MO, Al-Ali R, Karcher-Bausch S, Bozza M, Oezen I, Kramer M, Meyer J, Habel A, Eisel J, Poschet G, Weller M, Preusser M, Nadji-Ohl M, Thon N, Burger MC, Harter PN, Ratliff M, Harbottle R, Benner A, Schrimpf D, Okun J, Herold-Mende C, Turcan S, Kaulfuss S, Hess-Stumpp H, Bieback K, Cahill DP, Plate KH, Hänggi D, Dorsch M, Suvà ML, Niemeyer BA, von Deimling A, Wick W, Platten M. Bunse L, et al. Nat Med. 2018 Aug;24(8):1192-1203. doi: 10.1038/s41591-018-0095-6. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988124
Correlated magnetic resonance imaging and ultramicroscopy (MR-UM) is a tool kit to assess the dynamics of glioma angiogenesis.
Breckwoldt MO, Bode J, Kurz FT, Hoffmann A, Ochs K, Ott M, Deumelandt K, Krüwel T, Schwarz D, Fischer M, Helluy X, Milford D, Kirschbaum K, Solecki G, Chiblak S, Abdollahi A, Winkler F, Wick W, Platten M, Heiland S, Bendszus M, Tews B. Breckwoldt MO, et al. Elife. 2016 Feb 2;5:e11712. doi: 10.7554/eLife.11712. Elife. 2016. PMID: 26830460 Free PMC article.
K27M-mutant histone-3 as a novel target for glioma immunotherapy.
Ochs K, Ott M, Bunse T, Sahm F, Bunse L, Deumelandt K, Sonner JK, Keil M, von Deimling A, Wick W, Platten M. Ochs K, et al. Oncoimmunology. 2017 May 12;6(7):e1328340. doi: 10.1080/2162402X.2017.1328340. eCollection 2017. Oncoimmunology. 2017. PMID: 28811969 Free PMC article.
In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis.
Kirschbaum K, Sonner JK, Zeller MW, Deumelandt K, Bode J, Sharma R, Krüwel T, Fischer M, Hoffmann A, Costa da Silva M, Muckenthaler MU, Wick W, Tews B, Chen JW, Heiland S, Bendszus M, Platten M, Breckwoldt MO. Kirschbaum K, et al. Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13227-13232. doi: 10.1073/pnas.1609397113. Epub 2016 Oct 31. Proc Natl Acad Sci U S A. 2016. PMID: 27799546 Free PMC article.
The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas.
Sonner JK, Deumelandt K, Ott M, Thomé CM, Rauschenbach KJ, Schulz S, Munteanu B, Mohapatra S, Adam I, Hofer AC, Feuerer M, Opitz CA, Hopf C, Wick W, Platten M. Sonner JK, et al. Oncoimmunology. 2016 Nov 15;5(12):e1240858. doi: 10.1080/2162402X.2016.1240858. eCollection 2016. Oncoimmunology. 2016. PMID: 28123877 Free PMC article.
13 results