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Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer.
Kondelin J, Salokas K, Saarinen L, Ovaska K, Rauanheimo H, Plaketti RM, Hamberg J, Liu X, Yadav L, Gylfe AE, Cajuso T, Hänninen UA, Palin K, Ristolainen H, Katainen R, Kaasinen E, Tanskanen T, Aavikko M, Taipale M, Taipale J, Renkonen-Sinisalo L, Lepistö A, Koskensalo S, Böhm J, Mecklin JP, Ongen H, Dermitzakis ET, Kilpivaara O, Vahteristo P, Turunen M, Hautaniemi S, Tuupanen S, Karhu A, Välimäki N, Varjosalo M, Pitkänen E, Aaltonen LA. Kondelin J, et al. Among authors: dermitzakis et. EMBO Mol Med. 2018 Sep;10(9):e8552. doi: 10.15252/emmm.201708552. EMBO Mol Med. 2018. PMID: 30108113 Free PMC article.
Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer.
Øster B, Linnet L, Christensen LL, Thorsen K, Ongen H, Dermitzakis ET, Sandoval J, Moran S, Esteller M, Hansen TF, Lamy P; COLOFOL steering group; Laurberg S, Ørntoft TF, Andersen CL. Øster B, et al. Among authors: dermitzakis et. Int J Cancer. 2013 May 15;132(10):2303-15. doi: 10.1002/ijc.27921. Epub 2012 Nov 21. Int J Cancer. 2013. PMID: 23115050 Free article.
Putative cis-regulatory drivers in colorectal cancer.
Ongen H, Andersen CL, Bramsen JB, Oster B, Rasmussen MH, Ferreira PG, Sandoval J, Vidal E, Whiffin N, Planchon A, Padioleau I, Bielser D, Romano L, Tomlinson I, Houlston RS, Esteller M, Orntoft TF, Dermitzakis ET. Ongen H, et al. Among authors: dermitzakis et. Nature. 2014 Aug 7;512(7512):87-90. doi: 10.1038/nature13602. Epub 2014 Jul 23. Nature. 2014. PMID: 25079323
Fast and efficient QTL mapper for thousands of molecular phenotypes.
Ongen H, Buil A, Brown AA, Dermitzakis ET, Delaneau O. Ongen H, et al. Among authors: dermitzakis et. Bioinformatics. 2016 May 15;32(10):1479-85. doi: 10.1093/bioinformatics/btv722. Epub 2015 Dec 26. Bioinformatics. 2016. PMID: 26708335 Free PMC article.
SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism.
Christensen LL, True K, Hamilton MP, Nielsen MM, Damas ND, Damgaard CK, Ongen H, Dermitzakis E, Bramsen JB, Pedersen JS, Lund AH, Vang S, Stribolt K, Madsen MR, Laurberg S, McGuire SE, Ørntoft TF, Andersen CL. Christensen LL, et al. Mol Oncol. 2016 Oct;10(8):1266-82. doi: 10.1016/j.molonc.2016.06.003. Epub 2016 Jun 26. Mol Oncol. 2016. PMID: 27396952 Free PMC article.
The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression.
Liu NQ, Ter Huurne M, Nguyen LN, Peng T, Wang SY, Studd JB, Joshi O, Ongen H, Bramsen JB, Yan J, Andersen CL, Taipale J, Dermitzakis ET, Houlston RS, Hubner NC, Stunnenberg HG. Liu NQ, et al. Among authors: dermitzakis et. Nat Commun. 2017 Feb 14;8:14418. doi: 10.1038/ncomms14418. Nat Commun. 2017. PMID: 28195176 Free PMC article.
A complete tool set for molecular QTL discovery and analysis.
Delaneau O, Ongen H, Brown AA, Fort A, Panousis NI, Dermitzakis ET. Delaneau O, et al. Among authors: dermitzakis et. Nat Commun. 2017 May 18;8:15452. doi: 10.1038/ncomms15452. Nat Commun. 2017. PMID: 28516912 Free PMC article.
Estimating the causal tissues for complex traits and diseases.
Ongen H, Brown AA, Delaneau O, Panousis NI, Nica AC; GTEx Consortium; Dermitzakis ET. Ongen H, et al. Among authors: dermitzakis et. Nat Genet. 2017 Dec;49(12):1676-1683. doi: 10.1038/ng.3981. Epub 2017 Oct 23. Nat Genet. 2017. PMID: 29058715
252 results