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Antibody-based methods for the measurement of α-synuclein concentration in human cerebrospinal fluid - method comparison and round robin study.
Mollenhauer B, Bowman FD, Drake D, Duong J, Blennow K, El-Agnaf O, Shaw LM, Masucci J, Taylor P, Umek RM, Dunty JM, Smith CL, Stoops E, Vanderstichele H, Schmid AW, Moniatte M, Zhang J, Kruse N, Lashuel HA, Teunissen C, Schubert T, Dave KD, Hutten SJ, Zetterberg H. Mollenhauer B, et al. Among authors: dave kd. J Neurochem. 2019 Apr;149(1):126-138. doi: 10.1111/jnc.14569. Epub 2018 Nov 13. J Neurochem. 2019. PMID: 30125936 Free PMC article.
The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease.
Visanji NP, Mollenhauer B, Beach TG, Adler CH, Coffey CS, Kopil CM, Dave KD, Foroud T, Chahine L, Jennings D; Systemic Synuclein Sampling Study (S4). Visanji NP, et al. Among authors: dave kd. Biomark Med. 2017 Apr;11(4):359-368. doi: 10.2217/bmm-2016-0366. Epub 2017 Mar 29. Biomark Med. 2017. PMID: 28353371 Free article.
Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4).
Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbillé AG, Letournel F, Munoz DG, White CL 3rd, Schneider J, Crary JF, Sue LI, Adler CH, Glass MJ, Intorcia AJ, Walker JE, Foroud T, Coffey CS, Ecklund D, Riss H, Goßmann J, König F, Kopil CM, Arnedo V, Riley L, Linder C, Dave KD, Jennings D, Seibyl J, Mollenhauer B, Chahine L; Systemic Synuclein Sampling Study (S4). Beach TG, et al. Among authors: dave kd. J Neuropathol Exp Neurol. 2018 Sep 1;77(9):793-802. doi: 10.1093/jnen/nly056. J Neuropathol Exp Neurol. 2018. PMID: 30107604 Free PMC article.
Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4).
Chahine LM, Beach TG, Seedorff N, Caspell-Garcia C, Coffey CS, Brumm M, Adler CH, Serrano GE, Linder C, Mosovsky S, Foroud T, Riss H, Ecklund D, Seibyl J, Jennings D, Arnedo V, Riley L, Dave KD, Mollenhauer B; Systemic sSynuclein Sampling study. Chahine LM, et al. Among authors: dave kd. J Parkinsons Dis. 2018;8(4):517-527. doi: 10.3233/JPD-181434. J Parkinsons Dis. 2018. PMID: 30248065 Free PMC article.
A Proposed Roadmap for Parkinson's Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein.
Merchant KM, Cedarbaum JM, Brundin P, Dave KD, Eberling J, Espay AJ, Hutten SJ, Javidnia M, Luthman J, Maetzler W, Menalled L, Reimer AN, Stoessl AJ, Weiner DM; The Michael J. Fox Foundation Alpha Synuclein Clinical Path Working Group. Merchant KM, et al. Among authors: dave kd. J Parkinsons Dis. 2019;9(1):31-61. doi: 10.3233/JPD-181471. J Parkinsons Dis. 2019. PMID: 30400107 Free PMC article.
In vivo distribution of α-synuclein in multiple tissues and biofluids in Parkinson disease.
Chahine LM, Beach TG, Brumm MC, Adler CH, Coffey CS, Mosovsky S, Caspell-Garcia C, Serrano GE, Munoz DG, White CL 3rd, Crary JF, Jennings D, Taylor P, Foroud T, Arnedo V, Kopil CM, Riley L, Dave KD, Mollenhauer B; Systemic Synuclein Sampling Study. Chahine LM, et al. Among authors: dave kd. Neurology. 2020 Sep 1;95(9):e1267-e1284. doi: 10.1212/WNL.0000000000010404. Epub 2020 Aug 3. Neurology. 2020. PMID: 32747521 Free PMC article.
Central and peripheral α-synuclein in Parkinson disease detected by seed amplification assay.
Chahine LM, Beach TG, Adler CH, Hepker M, Kanthasamy A, Appel S, Pritzkow S, Pinho M, Mosovsky S, Serrano GE, Coffey C, Brumm MC, Oliveira LMA, Eberling J, Mollenhauer B; Systemic Synuclein Sampling Study. Chahine LM, et al. Ann Clin Transl Neurol. 2023 May;10(5):696-705. doi: 10.1002/acn3.51753. Epub 2023 Mar 27. Ann Clin Transl Neurol. 2023. PMID: 36972727 Free PMC article.
Therapeutic approaches to target alpha-synuclein pathology.
Brundin P, Dave KD, Kordower JH. Brundin P, et al. Among authors: dave kd. Exp Neurol. 2017 Dec;298(Pt B):225-235. doi: 10.1016/j.expneurol.2017.10.003. Epub 2017 Oct 4. Exp Neurol. 2017. PMID: 28987463 Free PMC article. Review.
31 results