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Inflammaging increases susceptibility to cigarette smoke-induced COPD.
John-Schuster G, Günter S, Hager K, Conlon TM, Eickelberg O, Yildirim AÖ. John-Schuster G, et al. Among authors: yildirim ao. Oncotarget. 2016 May 24;7(21):30068-83. doi: 10.18632/oncotarget.4027. Oncotarget. 2016. PMID: 26284585 Free PMC article.
Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice.
Jia J, Conlon TM, Ballester Lopez C, Seimetz M, Bednorz M, Zhou-Suckow Z, Weissmann N, Eickelberg O, Mall MA, Yildirim AÖ. Jia J, et al. Among authors: yildirim ao. Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L602-10. doi: 10.1152/ajplung.00124.2016. Epub 2016 Jul 22. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27448665 Free article.
Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease.
Jia J, Conlon TM, Sarker RS, Taşdemir D, Smirnova NF, Srivastava B, Verleden SE, Güneş G, Wu X, Prehn C, Gao J, Heinzelmann K, Lintelmann J, Irmler M, Pfeiffer S, Schloter M, Zimmermann R, Hrabé de Angelis M, Beckers J, Adamski J, Bayram H, Eickelberg O, Yildirim AÖ. Jia J, et al. Among authors: yildirim ao. EMBO Mol Med. 2018 May;10(5):e8349. doi: 10.15252/emmm.201708349. EMBO Mol Med. 2018. PMID: 29674392 Free PMC article.
Inhibition of LTβR signalling activates WNT-induced regeneration in lung.
Conlon TM, John-Schuster G, Heide D, Pfister D, Lehmann M, Hu Y, Ertüz Z, Lopez MA, Ansari M, Strunz M, Mayr C, Angelidis I, Ciminieri C, Costa R, Kohlhepp MS, Guillot A, Günes G, Jeridi A, Funk MC, Beroshvili G, Prokosch S, Hetzer J, Verleden SE, Alsafadi H, Lindner M, Burgstaller G, Becker L, Irmler M, Dudek M, Janzen J, Goffin E, Gosens R, Knolle P, Pirotte B, Stoeger T, Beckers J, Wagner D, Singh I, Theis FJ, de Angelis MH, O'Connor T, Tacke F, Boutros M, Dejardin E, Eickelberg O, Schiller HB, Königshoff M, Heikenwalder M, Yildirim AÖ. Conlon TM, et al. Among authors: yildirim ao. Nature. 2020 Dec;588(7836):151-156. doi: 10.1038/s41586-020-2882-8. Epub 2020 Nov 4. Nature. 2020. PMID: 33149305 Free PMC article.
A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration.
Wu X, Bos IST, Conlon TM, Ansari M, Verschut V, van der Koog L, Verkleij LA, D'Ambrosi A, Matveyenko A, Schiller HB, Königshoff M, Schmidt M, Kistemaker LEM, Yildirim AÖ, Gosens R. Wu X, et al. Among authors: yildirim ao. Sci Adv. 2022 Mar 25;8(12):eabj9949. doi: 10.1126/sciadv.abj9949. Epub 2022 Mar 23. Sci Adv. 2022. PMID: 35319981 Free PMC article.
Activation of the WNT/β-catenin pathway attenuates experimental emphysema.
Kneidinger N, Yildirim AÖ, Callegari J, Takenaka S, Stein MM, Dumitrascu R, Bohla A, Bracke KR, Morty RE, Brusselle GG, Schermuly RT, Eickelberg O, Königshoff M. Kneidinger N, et al. Among authors: yildirim ao. Am J Respir Crit Care Med. 2011 Mar 15;183(6):723-33. doi: 10.1164/rccm.200910-1560OC. Epub 2010 Oct 1. Am J Respir Crit Care Med. 2011. PMID: 20889911
209 results