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Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial.
Lancet. 2018 Sep 15;392(10151):940-949. doi: 10.1016/S0140-6736(18)31858-0. Epub 2018 Aug 27.
Lancet. 2018.
PMID: 30166073
Clinical Trial.
Ticagrelor Monotherapy or Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation: Per-Protocol Analysis of the GLOBAL LEADERS Trial.
Gragnano F, Zwahlen M, Vranckx P, Heg D, Schmidlin K, Hamm C, Steg PG, Gargiulo G, McFadden EP, Onuma Y, Chichareon P, Benit E, Möllmann H, Janssens L, Leonardi S, Zurakowski A, Arrivi A, Van Geuns RJ, Huber K, Slagboom T, Calabrò P, Serruys PW, Jüni P, Valgimigli M, Windecker S; GLOBAL LEADERS Investigators [Link].
Gragnano F, et al.
J Am Heart Assoc. 2022 May 17;11(10):e024291. doi: 10.1161/JAHA.121.024291. Epub 2022 Mar 1.
J Am Heart Assoc. 2022.
PMID: 35229616
Free PMC article.
Clinical Trial.
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Pertussis toxin relaxes small arteries with no vascular lesions or vascular smooth muscle cell injury.
van Meijeren CE, Vleeming W, Dormans JA, van de Kuil T, Opperhuizen A, Hendriksen CF, de Wildt DJ.
van Meijeren CE, et al.
Exp Toxicol Pathol. 2004 Dec;56(3):139-43. doi: 10.1016/j.etp.2004.07.003.
Exp Toxicol Pathol. 2004.
PMID: 15625782
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Pertussis toxin-induced histamine sensitisation: an aspecific phenomenon independent from the nitric oxide system?
van Meijeren CE, Vleeming W, van de Kuil T, Gerards AL, Hendriksen CF, de Wildt DJ.
van Meijeren CE, et al.
Eur J Pharmacol. 2004 Jun 16;493(1-3):139-50. doi: 10.1016/j.ejphar.2004.04.014.
Eur J Pharmacol. 2004.
PMID: 15189775
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In vivo pertussis toxin treatment reduces contraction of rat resistance arteries but not that of mouse trachea.
van Meijeren CE, Vleeming W, van de Kuil T, Manni J, Kegler D, Hendriksen CF, de Wildt DJ.
van Meijeren CE, et al.
Eur J Pharmacol. 2004 Mar 19;488(1-3):127-35. doi: 10.1016/j.ejphar.2004.02.003.
Eur J Pharmacol. 2004.
PMID: 15044044
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Comparison of in vitro preparations for semi-quantitative prediction of in vivo drug metabolism.
De Graaf IA, Van Meijeren CE, Pektaş F, Koster HJ.
De Graaf IA, et al. Among authors: van meijeren ce.
Drug Metab Dispos. 2002 Oct;30(10):1129-36. doi: 10.1124/dmd.30.10.1129.
Drug Metab Dispos. 2002.
PMID: 12228190
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