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Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.
Lenos KJ, Miedema DM, Lodestijn SC, Nijman LE, van den Bosch T, Romero Ros X, Lourenço FC, Lecca MC, van der Heijden M, van Neerven SM, van Oort A, Leveille N, Adam RS, de Sousa E Melo F, Otten J, Veerman P, Hypolite G, Koens L, Lyons SK, Stassi G, Winton DJ, Medema JP, Morrissey E, Bijlsma MF, Vermeulen L. Lenos KJ, et al. Among authors: koens l. Nat Cell Biol. 2018 Oct;20(10):1193-1202. doi: 10.1038/s41556-018-0179-z. Epub 2018 Sep 3. Nat Cell Biol. 2018. PMID: 30177776 Free PMC article.
Pre-Operative Decitabine in Colon Cancer Patients: Analyses on WNT Target Methylation and Expression.
Linnekamp JF, Kandimalla R, Fessler E, de Jong JH, Rodermond HM, van Bochove GGW, The FO, Punt CJA, Bemelman WA, van de Ven AWH, Tanis PJ, Kemper EM, Koens L, Dekker E, Vermeulen L, van Laarhoven HWM, Medema JP. Linnekamp JF, et al. Among authors: koens l. Cancers (Basel). 2021 May 13;13(10):2357. doi: 10.3390/cancers13102357. Cancers (Basel). 2021. PMID: 34068407 Free PMC article.
Apc-mutant cells act as supercompetitors in intestinal tumour initiation.
van Neerven SM, de Groot NE, Nijman LE, Scicluna BP, van Driel MS, Lecca MC, Warmerdam DO, Kakkar V, Moreno LF, Vieira Braga FA, Sanches DR, Ramesh P, Ten Hoorn S, Aelvoet AS, van Boxel MF, Koens L, Krawczyk PM, Koster J, Dekker E, Medema JP, Winton DJ, Bijlsma MF, Morrissey E, Léveillé N, Vermeulen L. van Neerven SM, et al. Among authors: koens l. Nature. 2021 Jun;594(7863):436-441. doi: 10.1038/s41586-021-03558-4. Epub 2021 Jun 2. Nature. 2021. PMID: 34079128
Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone.
Ten Hoorn S, Sommeijer DW, Elliott F, Fisher D, de Back TR, Trinh A, Koens L, Maughan T, Seligmann J, Seymour MT, Quirke P, Adams R, Richman SD, Punt CJA, Vermeulen L. Ten Hoorn S, et al. Among authors: koens l. Br J Cancer. 2021 Oct;125(8):1080-1088. doi: 10.1038/s41416-021-01477-9. Epub 2021 Jul 12. Br J Cancer. 2021. PMID: 34253874 Free PMC article.
Molecular characterization of colorectal cancer related peritoneal metastatic disease.
Lenos KJ, Bach S, Ferreira Moreno L, Ten Hoorn S, Sluiter NR, Bootsma S, Vieira Braga FA, Nijman LE, van den Bosch T, Miedema DM, van Dijk E, Ylstra B, Kulicke R, Davis FP, Stransky N, Smolen GA, Coebergh van den Braak RRJ, IJzermans JNM, Martens JWM, Hallam S, Beggs AD, Kops GJPL, Lansu N, Bastiaenen VP, Klaver CEL, Lecca MC, El Makrini K, Elbers CC, Dings MPG, van Noesel CJM, Kranenburg O, Medema JP, Koster J, Koens L, Punt CJA, Tanis PJ, de Hingh IH, Bijlsma MF, Tuynman JB, Vermeulen L. Lenos KJ, et al. Among authors: koens l. Nat Commun. 2022 Aug 4;13(1):4443. doi: 10.1038/s41467-022-32198-z. Nat Commun. 2022. PMID: 35927254 Free PMC article.
Programmed death-1 expression in cutaneous B-cell lymphoma.
Çetinözman F, Koens L, Jansen PM, Willemze R. Çetinözman F, et al. Among authors: koens l. J Cutan Pathol. 2014 Jan;41(1):14-21. doi: 10.1111/cup.12254. Epub 2013 Nov 23. J Cutan Pathol. 2014. PMID: 24151955
The occurrence and characteristics of endoscopically unexpected malignant degeneration in large rectal adenomas.
Bronzwaer MES, Musters GD, Barendse RM, Koens L, de Graaf EJR, Doornebosch PG, Schwartz MP, Consten ECJ, Schoon EJ, de Hingh IHJT, Tanis PJ, Dekker E, Fockens P; TREND study group. Bronzwaer MES, et al. Among authors: koens l. Gastrointest Endosc. 2018 Mar;87(3):862-871.e1. doi: 10.1016/j.gie.2017.09.046. Epub 2017 Oct 10. Gastrointest Endosc. 2018. PMID: 29030001 Clinical Trial.
Volume of surgery for benign colorectal polyps in the last 11 years.
Bronzwaer MES, Koens L, Bemelman WA, Dekker E, Fockens P; COPOS study group. Bronzwaer MES, et al. Among authors: koens l. Gastrointest Endosc. 2018 Feb;87(2):552-561.e1. doi: 10.1016/j.gie.2017.10.032. Epub 2017 Nov 3. Gastrointest Endosc. 2018. PMID: 29108978
73 results