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Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression.
Jiang Y, Jiang YY, Xie JJ, Mayakonda A, Hazawa M, Chen L, Xiao JF, Li CQ, Huang ML, Ding LW, Sun QY, Xu L, Kanojia D, Jeitany M, Deng JW, Liao LD, Soukiasian HJ, Berman BP, Hao JJ, Xu LY, Li EM, Wang MR, Bi XG, Lin DC, Koeffler HP. Jiang Y, et al. Among authors: chen l. Nat Commun. 2018 Sep 6;9(1):3619. doi: 10.1038/s41467-018-06081-9. Nat Commun. 2018. PMID: 30190462 Free PMC article.
Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.
Xie JJ, Jiang YY, Jiang Y, Li CQ, Lim MC, An O, Mayakonda A, Ding LW, Long L, Sun C, Lin LH, Chen L, Wu JY, Wu ZY, Cao Q, Fang WK, Yang W, Soukiasian H, Meltzer SJ, Yang H, Fullwood M, Xu LY, Li EM, Lin DC, Koeffler HP. Xie JJ, et al. Among authors: chen l. Gastroenterology. 2018 Jun;154(8):2137-2151.e1. doi: 10.1053/j.gastro.2018.02.018. Epub 2018 Feb 15. Gastroenterology. 2018. PMID: 29454790
Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma.
Chen L, Huang M, Plummer J, Pan J, Jiang YY, Yang Q, Silva TC, Gull N, Chen S, Ding LW, An O, Yang H, Cheng Y, Said JW, Doan N, Dinjens WN, Waters KM, Tuli R, Gayther SA, Klempner SJ, Berman BP, Meltzer SJ, Lin DC, Koeffler HP. Chen L, et al. Among authors: chen s. Gut. 2020 Apr;69(4):630-640. doi: 10.1136/gutjnl-2019-318325. Epub 2019 Aug 13. Gut. 2020. PMID: 31409603 Free PMC article.
Global functional analyses of cellular responses to pore-forming toxins.
Kao CY, Los FC, Huffman DL, Wachi S, Kloft N, Husmann M, Karabrahimi V, Schwartz JL, Bellier A, Ha C, Sagong Y, Fan H, Ghosh P, Hsieh M, Hsu CS, Chen L, Aroian RV. Kao CY, et al. Among authors: chen l. PLoS Pathog. 2011 Mar;7(3):e1001314. doi: 10.1371/journal.ppat.1001314. Epub 2011 Mar 3. PLoS Pathog. 2011. PMID: 21408619 Free PMC article.
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