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Page 1
Discovery of a new antileishmanial hit in 8-nitroquinoline series.
Paloque L, Verhaeghe P, Casanova M, Castera-Ducros C, Dumètre A, Mbatchi L, Hutter S, Kraiem-M'rabet M, Laget M, Remusat V, Rault S, Rathelot P, Azas N, Vanelle P. Paloque L, et al. Among authors: azas n. Eur J Med Chem. 2012 Aug;54:75-86. doi: 10.1016/j.ejmech.2012.04.029. Epub 2012 May 2. Eur J Med Chem. 2012. PMID: 22608675
Targeting the human parasite Leishmania donovani: discovery of a new promising anti-infectious pharmacophore in 3-nitroimidazo[1,2-a]pyridine series.
Castera-Ducros C, Paloque L, Verhaeghe P, Casanova M, Cantelli C, Hutter S, Tanguy F, Laget M, Remusat V, Cohen A, Crozet MD, Rathelot P, Azas N, Vanelle P. Castera-Ducros C, et al. Among authors: azas n. Bioorg Med Chem. 2013 Nov 15;21(22):7155-64. doi: 10.1016/j.bmc.2013.09.002. Epub 2013 Sep 11. Bioorg Med Chem. 2013. PMID: 24080103
Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium.
Cohen A, Suzanne P, Lancelot JC, Verhaeghe P, Lesnard A, Basmaciyan L, Hutter S, Laget M, Dumètre A, Paloque L, Deharo E, Crozet MD, Rathelot P, Dallemagne P, Lorthiois A, Sibley CH, Vanelle P, Valentin A, Mazier D, Rault S, Azas N. Cohen A, et al. Among authors: azas n. Eur J Med Chem. 2015 May 5;95:16-28. doi: 10.1016/j.ejmech.2015.03.011. Epub 2015 Mar 10. Eur J Med Chem. 2015. PMID: 25791675
Design, synthesis and antimalarial activity of novel bis{N-[(pyrrolo[1,2-a]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives.
Guillon J, Cohen A, Gueddouda NM, Das RN, Moreau S, Ronga L, Savrimoutou S, Basmaciyan L, Monnier A, Monget M, Rubio S, Garnerin T, Azas N, Mergny JL, Mullié C, Sonnet P. Guillon J, et al. Among authors: azas n. J Enzyme Inhib Med Chem. 2017 Dec;32(1):547-563. doi: 10.1080/14756366.2016.1268608. J Enzyme Inhib Med Chem. 2017. PMID: 28114821 Free PMC article.
Calcein+/PI- as an early apoptotic feature in Leishmania.
Basmaciyan L, Azas N, Casanova M. Basmaciyan L, et al. Among authors: azas n. PLoS One. 2017 Nov 7;12(11):e0187756. doi: 10.1371/journal.pone.0187756. eCollection 2017. PLoS One. 2017. PMID: 29112976 Free PMC article.
Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives.
Guillon J, Cohen A, Das RN, Boudot C, Gueddouda NM, Moreau S, Ronga L, Savrimoutou S, Basmaciyan L, Tisnerat C, Mestanier S, Rubio S, Amaziane S, Dassonville-Klimpt A, Azas N, Courtioux B, Mergny JL, Mullié C, Sonnet P. Guillon J, et al. Among authors: azas n. Chem Biol Drug Des. 2018 May;91(5):974-995. doi: 10.1111/cbdd.13164. Epub 2018 Jan 17. Chem Biol Drug Des. 2018. PMID: 29266861
Different apoptosis pathways in Leishmania parasites.
Basmaciyan L, Azas N, Casanova M. Basmaciyan L, et al. Among authors: azas n. Cell Death Discov. 2018 Aug 20;4:27. doi: 10.1038/s41420-018-0092-z. eCollection 2018. Cell Death Discov. 2018. PMID: 30155277 Free PMC article. No abstract available.
96 results