Leffler A - Search Results

1

Etomidate and propylene glycol activate nociceptive TRP ion channels.

Niedermirtl F, Eberhardt M, Namer B, Leffler A, Nau C, Reeh PW, Kistner K. Niedermirtl F, et al. Among authors: leffler a. Mol Pain. 2018 Jan-Dec;14:1744806918811699. doi: 10.1177/1744806918811699. Epub 2018 Oct 22. Mol Pain. 2018. PMID: 30345869 Free PMC article.

2

The TRPV1/2/3 activator 2-aminoethoxydiphenyl borate sensitizes native nociceptive neurons to heat in wildtype but not TRPV1 deficient mice.

Zimmermann K, Leffler A, Fischer MM, Messlinger K, Nau C, Reeh PW. Zimmermann K, et al. Among authors: leffler a. Neuroscience. 2005;135(4):1277-84. doi: 10.1016/j.neuroscience.2005.07.018. Epub 2005 Sep 13. Neuroscience. 2005. PMID: 16165301

3

Use-dependent block by lidocaine but not amitriptyline is more pronounced in tetrodotoxin (TTX)-Resistant Nav1.8 than in TTX-sensitive Na+ channels.

Leffler A, Reiprich A, Mohapatra DP, Nau C. Leffler A, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):354-64. doi: 10.1124/jpet.106.109025. Epub 2006 Sep 27. J Pharmacol Exp Ther. 2007. PMID: 17005919

4

Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures.

Zimmermann K, Leffler A, Babes A, Cendan CM, Carr RW, Kobayashi J, Nau C, Wood JN, Reeh PW. Zimmermann K, et al. Among authors: leffler a. Nature. 2007 Jun 14;447(7146):855-8. doi: 10.1038/nature05880. Nature. 2007. PMID: 17568746

5

A high-threshold heat-activated channel in cultured rat dorsal root ganglion neurons resembles TRPV2 and is blocked by gadolinium.

Leffler A, Linte RM, Nau C, Reeh P, Babes A. Leffler A, et al. Eur J Neurosci. 2007 Jul;26(1):12-22. doi: 10.1111/j.1460-9568.2007.05643.x. Epub 2007 Jun 26. Eur J Neurosci. 2007. PMID: 17596195

6

The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons.

Leffler A, Fischer MJ, Rehner D, Kienel S, Kistner K, Sauer SK, Gavva NR, Reeh PW, Nau C. Leffler A, et al. J Clin Invest. 2008 Feb;118(2):763-76. doi: 10.1172/JCI32751. J Clin Invest. 2008. PMID: 18172555 Free PMC article.

7

Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites.

Leffler A, Reckzeh J, Nau C. Leffler A, et al. Eur J Pharmacol. 2010 Mar 25;630(1-3):19-28. doi: 10.1016/j.ejphar.2009.12.027. Epub 2010 Jan 4. Eur J Pharmacol. 2010. PMID: 20044988

8

Sodium channelopathies and pain.

Lampert A, O'Reilly AO, Reeh P, Leffler A. Lampert A, et al. Among authors: leffler a. Pflugers Arch. 2010 Jul;460(2):249-63. doi: 10.1007/s00424-009-0779-3. Epub 2010 Jan 26. Pflugers Arch. 2010. PMID: 20101409 Review.

9

The tetrodotoxin-resistant Na+ channel Na (v)1.8 reduces the potency of local anesthetics in blocking C-fiber nociceptors.

Kistner K, Zimmermann K, Ehnert C, Reeh PW, Leffler A. Kistner K, et al. Among authors: leffler a. Pflugers Arch. 2010 Apr;459(5):751-63. doi: 10.1007/s00424-010-0785-5. Epub 2010 Feb 23. Pflugers Arch. 2010. PMID: 20174994

10

The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors.

Fischer MJ, Leffler A, Niedermirtl F, Kistner K, Eberhardt M, Reeh PW, Nau C. Fischer MJ, et al. Among authors: leffler a. J Biol Chem. 2010 Nov 5;285(45):34781-92. doi: 10.1074/jbc.M110.143958. Epub 2010 Sep 7. J Biol Chem. 2010. PMID: 20826794 Free PMC article.

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