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Reaction of dopa decarboxylase with alpha-methyldopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active site directed affinity label.
Bertoldi M, Dominici P, Moore PS, Maras B, Voltattorni CB. Bertoldi M, et al. Biochemistry. 1998 May 5;37(18):6552-61. doi: 10.1021/bi9718898. Biochemistry. 1998. PMID: 9572873
As recently reported for serotonin (5-HT) [Bertoldi, M., Moore, P. S., Maras, B., Dominici, P., and Borri Voltattorni, C. (1996) J. ...
As recently reported for serotonin (5-HT) [Bertoldi, M., Moore, P. S., Maras, B., Dominici, P., and Borri Voltattorni, C. (199 …
Ornithine and glutamate decarboxylases catalyse an oxidative deamination of their alpha-methyl substrates.
Bertoldi M, Carbone V, Borri Voltattorni C. Bertoldi M, et al. Biochem J. 1999 Sep 15;342 Pt 3(Pt 3):509-12. Biochem J. 1999. PMID: 10477260 Free PMC article.
Molecular oxygen was consumed during these reactions in a 1:2 molar ratio with respect to the products. The catalytic efficiencies (k(cat)/K(m)) of the reactions catalysed by ODC and GAD were determined as 12500 and 9163 M(-1).min(-1) respectively. ...Taken together …
Molecular oxygen was consumed during these reactions in a 1:2 molar ratio with respect to the products. The catalytic efficiencies (k(cat)/K …
143 results