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Biodegradable Amphipathic Peptide Hydrogels as Extended-Release System for Opioid Peptides.
Martin C, Dumitrascuta M, Mannes M, Lantero A, Bucher D, Walker K, Van Wanseele Y, Oyen E, Hernot S, Van Eeckhaut A, Madder A, Hoogenboom R, Spetea M, Ballet S. Martin C, et al. Among authors: mannes m. J Med Chem. 2018 Nov 8;61(21):9784-9789. doi: 10.1021/acs.jmedchem.8b01282. Epub 2018 Oct 26. J Med Chem. 2018. PMID: 30351003
Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release.
Heremans J, Chevillard L, Mannes M, Mangialetto J, Leroy K, White JF, Lamouroux A, Vinken M, Gardiner J, Van Mele B, Van den Brande N, Hoogenboom R, Madder A, Caveliers V, Mégarbane B, Hernot S, Ballet S, Martin C. Heremans J, et al. Among authors: mannes m. J Control Release. 2022 Oct;350:514-524. doi: 10.1016/j.jconrel.2022.08.027. Epub 2022 Sep 1. J Control Release. 2022. PMID: 35998769
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design.
Gimenez LE, Martin C, Yu J, Hollanders C, Hernandez CC, Wu Y, Yao D, Han GW, Dahir NS, Wu L, Van der Poorten O, Lamouroux A, Mannes M, Zhao S, Tourwé D, Stevens RC, Cone RD, Ballet S. Gimenez LE, et al. Among authors: mannes m. J Med Chem. 2024 Feb 22;67(4):2690-2711. doi: 10.1021/acs.jmedchem.3c01822. Epub 2024 Feb 12. J Med Chem. 2024. PMID: 38345933
Triple-fusion protein (TriFu): A potent, targeted, enzyme-like inhibitor of all three complement activation pathways.
Sonnentag SJ, Dopler A, Kleiner K, Garg BK, Mannes M, Späth N, Akilah A, Höchsmann B, Schrezenmeier H, Anliker M, Boyanapalli R, Huber-Lang M, Schmidt CQ. Sonnentag SJ, et al. Among authors: mannes m. J Biol Chem. 2024 Apr;300(4):105784. doi: 10.1016/j.jbc.2024.105784. Epub 2024 Feb 23. J Biol Chem. 2024. PMID: 38401844 Free PMC article.
Soluble terminal complement complex blood levels are elevated in schizophrenia.
Savukoski S, Mannes M, Wohlgemuth L, Schultze A, Guest PC, Meyer-Lotz G, Dobrowolny H, Relja B, Huber-Lang M, Steiner J. Savukoski S, et al. Among authors: mannes m. Eur Arch Psychiatry Clin Neurosci. 2024 Jan 19. doi: 10.1007/s00406-023-01738-z. Online ahead of print. Eur Arch Psychiatry Clin Neurosci. 2024. PMID: 38243017
27 results