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Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.
Duffy DJ, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, Mehta JP, Killick K, Whilde J, Turriziani B, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W. Duffy DJ, et al. Among authors: kolch w. Oncotarget. 2015 Dec 22;6(41):43182-201. doi: 10.18632/oncotarget.6568. Oncotarget. 2015. PMID: 26673823 Free PMC article.
Wnt signalling is a bi-directional vulnerability of cancer cells.
Duffy DJ, Krstic A, Schwarzl T, Halasz M, Iljin K, Fey D, Haley B, Whilde J, Haapa-Paananen S, Fey V, Fischer M, Westermann F, Henrich KO, Bannert S, Higgins DG, Kolch W. Duffy DJ, et al. Among authors: kolch w. Oncotarget. 2016 Sep 13;7(37):60310-60331. doi: 10.18632/oncotarget.11203. Oncotarget. 2016. PMID: 27531891 Free PMC article.
304 results