Chen Y - Search Results

1

Aberrant Activation of β-Catenin Signaling Drives Glioma Tumorigenesis via USP1-Mediated Stabilization of EZH2.

Ma L, Lin K, Chang G, Chen Y, Yue C, Guo Q, Zhang S, Jia Z, Huang TT, Zhou A, Huang S. Ma L, et al. Among authors: chen y. Cancer Res. 2019 Jan 1;79(1):72-85. doi: 10.1158/0008-5472.CAN-18-1304. Epub 2018 Nov 13. Cancer Res. 2019. PMID: 30425057 Free PMC article.

2

Integrative Analysis Reveals the Transcriptional Collaboration between EZH2 and E2F1 in the Regulation of Cancer-Related Gene Expression.

Xu H, Xu K, He HH, Zang C, Chen CH, Chen Y, Qin Q, Wang S, Wang C, Hu S, Li F, Long H, Brown M, Liu XS. Xu H, et al. Among authors: chen ch, chen y. Mol Cancer Res. 2016 Feb;14(2):163-172. doi: 10.1158/1541-7786.MCR-15-0313. Epub 2015 Dec 9. Mol Cancer Res. 2016. PMID: 26659825 Free PMC article.

3

FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.

Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM. Nguyen TM, et al. Among authors: chen y. Cancer Res. 2018 Aug 1;78(15):4229-4240. doi: 10.1158/0008-5472.CAN-18-0631. Epub 2018 May 29. Cancer Res. 2018. PMID: 29844125 Free PMC article.

4

Critical role of lncEPAT in coupling dysregulated EGFR pathway and histone H2A deubiquitination during glioblastoma tumorigenesis.

Li L, Zhou A, Wei Y, Liu F, Li P, Fang R, Ma L, Zhang S, Wang L, Liu J, Richard HT, Chen Y, Wang H, Huang S. Li L, et al. Among authors: chen y. Sci Adv. 2022 Oct 7;8(40):eabn2571. doi: 10.1126/sciadv.abn2571. Epub 2022 Oct 5. Sci Adv. 2022. PMID: 36197973 Free PMC article.

5

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.

Zheng C, Wei Y, Zhang P, Xu L, Zhang Z, Lin K, Hou J, Lv X, Ding Y, Chiu Y, Jain A, Islam N, Malovannaya A, Wu Y, Ding F, Xu H, Sun M, Chen X, Chen Y. Zheng C, et al. Among authors: chen x, chen y. J Clin Invest. 2023 Mar 1;133(5):e159940. doi: 10.1172/JCI159940. J Clin Invest. 2023. PMID: 36856111 Free PMC article.

6

Multiomics analyses reveal DARS1-AS1/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance.

Zheng C, Wei Y, Zhang Q, Sun M, Wang Y, Hou J, Zhang P, Lv X, Su D, Jiang Y, Gumin J, Sahni N, Hu B, Wang W, Chen X, McGrail DJ, Zhang C, Huang S, Xu H, Chen J, Lang FF, Hu J, Chen Y. Zheng C, et al. Among authors: chen j, chen x, chen y. Sci Adv. 2023 Aug 4;9(31):eadf3984. doi: 10.1126/sciadv.adf3984. Epub 2023 Aug 4. Sci Adv. 2023. PMID: 37540752 Free PMC article.

7

CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.

Zheng C, Wei Y, Zhang P, Lin K, He D, Teng H, Manyam G, Zhang Z, Liu W, Lee HRL, Tang X, He W, Islam N, Jain A, Chiu Y, Cao S, Diao Y, Meyer-Gauen S, Höök M, Malovannaya A, Li W, Hu M, Wang W, Xu H, Kopetz S, Chen Y. Zheng C, et al. Among authors: chen y. Nat Struct Mol Biol. 2023 Dec;30(12):1878-1892. doi: 10.1038/s41594-023-01117-1. Epub 2023 Nov 6. Nat Struct Mol Biol. 2023. PMID: 37932451 Free PMC article.

8

Targeting androgen receptor in estrogen receptor-negative breast cancer.

Ni M, Chen Y, Lim E, Wimberly H, Bailey ST, Imai Y, Rimm DL, Liu XS, Brown M. Ni M, et al. Among authors: chen y. Cancer Cell. 2011 Jul 12;20(1):119-31. doi: 10.1016/j.ccr.2011.05.026. Cancer Cell. 2011. PMID: 21741601 Free PMC article.

9

A comprehensive view of nuclear receptor cancer cistromes.

Tang Q, Chen Y, Meyer C, Geistlinger T, Lupien M, Wang Q, Liu T, Zhang Y, Brown M, Liu XS. Tang Q, et al. Among authors: chen y. Cancer Res. 2011 Nov 15;71(22):6940-7. doi: 10.1158/0008-5472.CAN-11-2091. Epub 2011 Sep 22. Cancer Res. 2011. PMID: 21940749 Free PMC article.

10

Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.

Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Zhao N, et al. Among authors: chen x, chen y. J Clin Invest. 2018 Apr 2;128(4):1283-1299. doi: 10.1172/JCI95873. Epub 2018 Feb 26. J Clin Invest. 2018. PMID: 29480818 Free PMC article.

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