van Riggelen J - Search Results

1

Targeting the MYC Oncogene in Burkitt Lymphoma through HSP90 Inhibition.

Poole CJ, Zheng W, Lee H, Young D, Lodh A, Chadli A, van Riggelen J. Poole CJ, et al. Among authors: van riggelen j. Cancers (Basel). 2018 Nov 16;10(11):448. doi: 10.3390/cancers10110448. Cancers (Basel). 2018. PMID: 30453475 Free PMC article.

2

DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma.

Poole CJ, Zheng W, Lodh A, Yevtodiyenko A, Liefwalker D, Li H, Felsher DW, van Riggelen J. Poole CJ, et al. Among authors: van riggelen j. Oncotarget. 2017 Aug 10;8(44):76898-76920. doi: 10.18632/oncotarget.20176. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100357 Free PMC article.

3

FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome.

Hu T, Wu Q, Chong Y, Qin H, Poole CJ, van Riggelen J, Ren M, Cowell JK. Hu T, et al. Among authors: van riggelen j. Leukemia. 2018 Nov;32(11):2363-2373. doi: 10.1038/s41375-018-0124-y. Epub 2018 Apr 2. Leukemia. 2018. PMID: 29720732 Free PMC article.

4

MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL.

Poole CJ, Lodh A, Choi JH, van Riggelen J. Poole CJ, et al. Among authors: van riggelen j. Epigenetics Chromatin. 2019 Jul 2;12(1):41. doi: 10.1186/s13072-019-0278-5. Epigenetics Chromatin. 2019. PMID: 31266538 Free PMC article.

5

MYC-Master Regulator of the Cancer Epigenome and Transcriptome.

Poole CJ, van Riggelen J. Poole CJ, et al. Among authors: van riggelen j. Genes (Basel). 2017 May 13;8(5):142. doi: 10.3390/genes8050142. Genes (Basel). 2017. PMID: 28505071 Free PMC article. Review.

6

Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity.

Alptekin A, Ye B, Yu Y, Poole CJ, van Riggelen J, Zha Y, Ding HF. Alptekin A, et al. Among authors: van riggelen j. Oncogene. 2019 Dec;38(50):7504-7520. doi: 10.1038/s41388-019-0967-3. Epub 2019 Aug 23. Oncogene. 2019. PMID: 31444411 Free PMC article.

7

Expression regulation and function of PD-1 and PD-L1 in T lymphoma cells.

Liu MY, Klement JD, Langan CJ, van Riggelen J, Liu K. Liu MY, et al. Among authors: van riggelen j. Cell Immunol. 2021 Aug;366:104397. doi: 10.1016/j.cellimm.2021.104397. Epub 2021 Jun 17. Cell Immunol. 2021. PMID: 34157461 Free PMC article.

8

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation.

Wu CH, van Riggelen J, Yetil A, Fan AC, Bachireddy P, Felsher DW. Wu CH, et al. Among authors: van riggelen j. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13028-33. doi: 10.1073/pnas.0701953104. Epub 2007 Jul 30. Proc Natl Acad Sci U S A. 2007. PMID: 17664422 Free PMC article.

9

MYC as a regulator of ribosome biogenesis and protein synthesis.

van Riggelen J, Yetil A, Felsher DW. van Riggelen J, et al. Nat Rev Cancer. 2010 Apr;10(4):301-9. doi: 10.1038/nrc2819. Nat Rev Cancer. 2010. PMID: 20332779 Review.

10

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia.

Yetil A, Anchang B, Gouw AM, Adam SJ, Zabuawala T, Parameswaran R, van Riggelen J, Plevritis S, Felsher DW. Yetil A, et al. Among authors: van riggelen j. Oncotarget. 2015 Feb 28;6(6):3563-77. doi: 10.18632/oncotarget.2969. Oncotarget. 2015. PMID: 25784651 Free PMC article.

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