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Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase.
McGowan S, Porter CJ, Lowther J, Stack CM, Golding SJ, Skinner-Adams TS, Trenholme KR, Teuscher F, Donnelly SM, Grembecka J, Mucha A, Kafarski P, Degori R, Buckle AM, Gardiner DL, Whisstock JC, Dalton JP. McGowan S, et al. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2537-42. doi: 10.1073/pnas.0807398106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196988 Free PMC article.
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials.
Skinner-Adams TS, Stack CM, Trenholme KR, Brown CL, Grembecka J, Lowther J, Mucha A, Drag M, Kafarski P, McGowan S, Whisstock JC, Gardiner DL, Dalton JP. Skinner-Adams TS, et al. Among authors: mcgowan s. Trends Biochem Sci. 2010 Jan;35(1):53-61. doi: 10.1016/j.tibs.2009.08.004. Epub 2009 Sep 30. Trends Biochem Sci. 2010. PMID: 19796954 Review.
Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases.
McGowan S, Oellig CA, Birru WA, Caradoc-Davies TT, Stack CM, Lowther J, Skinner-Adams T, Mucha A, Kafarski P, Grembecka J, Trenholme KR, Buckle AM, Gardiner DL, Dalton JP, Whisstock JC. McGowan S, et al. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2449-54. doi: 10.1073/pnas.0911813107. Epub 2010 Jan 21. Proc Natl Acad Sci U S A. 2010. PMID: 20133789 Free PMC article.
447 results